HitPredict

Interactor 1: ERP29 (P30040)
Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31)
Gene: ERP29

Interactor 2: CALR3 (Q96L12)
Calreticulin-3 (Calreticulin-2) (Calsperin)
Gene: CALR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31056421, 34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Calreticulin~ERp29
Common GO terms	GO:0005788 - endoplasmic reticulum lumen GO:0006457 - protein folding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 261 Hs			1 384
+	Hs
		653488 ERP29_HUMAN (1-261): 6.75e-81: 245: 100.00		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	Hs
		671897 PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		1067796 PDIA6_HUMAN (13-251): 1.66e-29: 116: 17.48		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		423330 PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		531950 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		1240407 TXND5_HUMAN (57-255): 6.77e-20: 89.8: 15.27		CALR3_HUMAN (1-384): 0: 543: 100.00
+	Hs
		654095 ERP29_HUMAN (1-261): 6.75e-81: 245: 100.00		CALX_HUMAN (16-357): 7.28e-123: 368: 26.73
+	Hs
		653491 PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	Hs
		653597 PDIA6_HUMAN (13-251): 1.66e-29: 116: 17.48		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	Hs
		531728 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	Hs
		653575 PDIA2_HUMAN (23-151): 1.93e-27: 112: 16.67		CALR_HUMAN (18-348): 5e-156: 447: 51.88
+	At
		137900 PDI21_ARATH (41-211): 1.27e-31: 121: 18.97		CALR1_ARATH (3-341): 3.11e-144: 417: 38.94
+	Dm
		667020 Q3YMU0_DROME (28-150): 2.02e-25: 106: 13.49		CALR_DROME (8-365): 2.58e-144: 417: 41.56
+	Dm
		667040 PDIA6_DROME (15-137): 9.87e-24: 101: 15.08		CALR_DROME (8-365): 2.58e-144: 417: 41.56
+	Dm
		667013 PDI_DROME (16-209): 9.63e-19: 87.1: 19.70		CALR_DROME (8-365): 2.58e-144: 417: 41.56
+	Hs
		654099 PDIA3_HUMAN (28-150): 5.13e-30: 119: 13.49		CALX_HUMAN (16-357): 7.28e-123: 368: 26.73
+	Rn
		514119 PDIA3_RAT (28-150): 1.38e-28: 115: 12.70		CALX_RAT (16-357): 1.96e-122: 367: 26.97
+	Hs
		423150 PDIA1_HUMAN (34-150): 7.83e-28: 112: 14.17		CALX_HUMAN (16-357): 7.28e-123: 368: 26.73
+	Hs
		531729 PDIA4_HUMAN (24-154): 1.36e-27: 112: 17.78		CALX_HUMAN (16-357): 7.28e-123: 368: 26.73
+	Dm
		1359553 PDIA6_DROME (15-137): 9.87e-24: 101: 15.08		Q9VAL7_DROME (22-355): 4.6e-120: 362: 26.51