HitPredict

Interactor 1: A0A087WW66 (A0A087WW66)
26S proteasome non-ATPase regulatory subunit 1
Gene: PSMD1

Interactor 2: PSD11 (O00231)
26S proteasome non-ATPase regulatory subunit 11 (26S proteasome regulatory subunit RPN6) (26S proteasome regulatory subunit S9) (26S proteasome regulatory subunit p44.5)
Gene: PSMD11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 914 Hs			1 422
+	Hs
		121840 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00
+	Hs
		706 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Hs
		1062862 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	Hs
		678 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86
+	Hs
		122075 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86
+	Dm
		1180713 PSMD1_DROME (2-894): 0: 1056: 58.84		PSD11_DROME (4-422): 6.96e-107: 323: 67.46
+	Dm
		1358522 PSMD1_DROME (2-894): 0: 1056: 58.84		PSMD6_DROME (31-422): 3.38e-72: 233: 13.93
+	Sc
		693378 RPN2_YEAST (2-914): 0: 919: 38.04		RPN6_YEAST (39-421): 4.48e-81: 257: 45.36
+	Hs
		121748 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSD11_HUMAN (1-422): 1.54e-117: 351: 100.00
+	Hs
		1027653 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSMD6_HUMAN (31-422): 3.57e-77: 246: 13.68
+	At
		1338956 PSD2A_ARATH (8-713): 0: 647: 17.93		PSD11_ARATH (10-421): 4.55e-96: 295: 51.94
+	Dm
		1180725 Q9VW54_DROME (12-712): 0: 614: 18.02		PSD11_DROME (4-422): 6.96e-107: 323: 67.46
+	Hs
		121998 PSMD2_HUMAN (8-712): 0: 704: 20.00		PSD12_HUMAN (46-422): 1.57e-66: 220: 12.86
+	At
		1275272 PSD2A_ARATH (8-713): 0: 647: 17.93		PSMD6_ARATH (34-422): 8.51e-66: 216: 14.71
+	Sp
		953211 RPN1_SCHPO (8-755): 0: 574: 17.61		RPN6_SCHPO (13-419): 1.56e-91: 284: 54.90
+	Dm
		1358535 Q9VW54_DROME (12-712): 0: 614: 18.02		PSMD6_DROME (31-422): 3.38e-72: 233: 13.93
+	Sp
		953207 RPN1_SCHPO (8-755): 0: 574: 17.61		RPN7_SCHPO (55-420): 1.19e-53: 185: 12.96
+	Sc
		753987 RPN1_YEAST (8-604): 2.05e-149: 468: 15.96		RPN6_YEAST (39-421): 4.48e-81: 257: 45.36