HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: SOX6 (P35712)
Transcription factor SOX-6
Gene: SOX6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 828
+	Hs
		727932 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		SOX6_HUMAN (1-828): 0: 640: 100.00
+	Hs
		727811 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		SOX5_HUMAN (1-789): 5.72e-135: 421: 55.79
+	Hs
		128153 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		SSRP1_HUMAN (257-792): 1.33e-37: 152: 12.45
+	Hs
		127951 IF2B3_HUMAN (1-579): 2.3e-149: 444: 100.00		SOX15_HUMAN (619-698): 7.32e-33: 128: 52.50
+	Hs
		996938 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		SSRP1_HUMAN (257-792): 1.33e-37: 152: 12.45
+	Hs
		818543 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02
+	Hs
		225797 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		SOX15_HUMAN (619-698): 7.32e-33: 128: 52.50
+	Hs
		1071975 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		CIC_HUMAN (323-827): 1.48e-39: 161: 15.33
+	Hs
		1072162 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		CIC_HUMAN (323-827): 1.48e-39: 161: 15.33
+	Mm
		818750 FUBP1_MOUSE (342-559): 8.33e-30: 126: 23.32		SOX2_MOUSE (582-707): 1.37e-36: 142: 38.10
+	Hs
		818673 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02
+	Hs
		818352 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02
+	Hs
		233835 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		HBP1_HUMAN (515-703): 1.53e-36: 146: 23.28
+	Hs
		818011 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		SOX2_HUMAN (587-707): 3.88e-37: 144: 38.02
+	Mm
		818703 FUBP2_MOUSE (458-567): 9.99e-13: 73.1: 20.00		SOX2_MOUSE (582-707): 1.37e-36: 142: 38.10
+	Mm
		818701 Q3TIX6_MOUSE (467-564): 4.65e-11: 67.3: 14.29		SOX2_MOUSE (582-707): 1.37e-36: 142: 38.10