HitPredict

Interactor 1: GDIA (P31150)
Rab GDP dissociation inhibitor alpha (Rab GDI alpha) (Guanosine diphosphate dissociation inhibitor 1) (GDI-1) (Oligophrenin-2) (Protein XAP-4)
Gene: GDI1

Interactor 2: RAB1A (P62820)
Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein)
Gene: RAB1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.90	1.00	0.950

Property	Details
Experiments	28514442, 33961781, 35271311, 35343654, 26496610, 19942850
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 447 Hs			1 205
+	Mm
		838709 GDIA_MOUSE (1-447): 0: 722: 97.99		RAB1A_MOUSE (1-205): 4.45e-92: 269: 100.00
+	Hs
		678381 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		678394 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		678343 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		838625 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1A_HUMAN (1-205): 4.45e-92: 269: 100.00
+	Hs
		678359 GDIA_HUMAN (1-447): 0: 724: 100.00		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		678336 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		678341 GDIA_HUMAN (1-447): 0: 724: 100.00		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Hs
		838673 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB8B_HUMAN (4-203): 8.94e-88: 258: 52.00
+	Hs
		838683 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB1B_HUMAN (4-205): 5.68e-86: 254: 92.08
+	Hs
		838624 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11A_HUMAN (1-205): 3.52e-83: 247: 44.60
+	Hs
		838647 GDIB_HUMAN (1-444): 0: 700: 86.49		RB11B_HUMAN (1-205): 1.3e-81: 243: 44.19
+	Hs
		838616 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB8A_HUMAN (4-203): 3.82e-81: 242: 54.00
+	Hs
		838621 GDIB_HUMAN (1-444): 0: 700: 86.49		RAB14_HUMAN (1-205): 3.15e-81: 242: 41.86
+	Dm
		185501 Q9VLB7_DROME (1-440): 0: 657: 67.80		O18332_DROME (1-205): 5.89e-86: 254: 82.93
+	Dm
		185708 Q9VLB7_DROME (1-440): 0: 657: 67.80		O18335_DROME (1-205): 2.98e-81: 242: 45.07
+	Sc
		350882 GDI1_YEAST (1-429): 0: 590: 55.05		YPT1_YEAST (4-205): 8.39e-81: 240: 70.39
+	Dm
		185694 RABEP_DROME (1-424): 3.13e-134: 397: 24.19		O18335_DROME (1-205): 2.98e-81: 242: 45.07
+	Sc
		350859 RAEP_YEAST (2-374): 4.73e-121: 367: 26.13		YPT1_YEAST (4-205): 8.39e-81: 240: 70.39
+	At
		656917 REP_ARATH (2-433): 2.71e-90: 286: 20.26		RAE1C_ARATH (7-205): 6.14e-88: 259: 57.28