HitPredict

Interactor 1: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 330 Hs			1 651
+	Hs
		211976 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		BRD7_HUMAN (1-651): 1.84e-168: 498: 100.00
+	Hs
		679102 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		679149 TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		1315222 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		CECR2_HUMAN (79-519): 1.47e-52: 198: 17.62
+	Hs
		999101 NANOG_HUMAN (133-316): 2.34e-38: 140: 25.89		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Rn
		94370 PIT1_RAT (8-267): 2.92e-36: 133: 13.26		F1M9G7_RAT (25-251): 1.85e-42: 167: 22.27
+	Hs
		656411 PIT1_HUMAN (8-267): 3.12e-37: 136: 13.64		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		1270832 PO2F3_HUMAN (20-326): 2.73e-35: 134: 16.40		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		211845 TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		568035 HXB6_HUMAN (58-279): 7.84e-35: 128: 23.42		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		882125 GSC_HUMAN (58-285): 5.34e-30: 116: 20.61		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		446868 HXD4_HUMAN (62-301): 8.84e-30: 115: 23.33		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		567914 HXB4_HUMAN (36-261): 5.5e-32: 121: 21.05		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		453059 HXB7_HUMAN (43-271): 4.77e-32: 120: 21.83		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Mm
		590398 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		TAF1_MOUSE (58-534): 2.79e-36: 148: 14.52
+	Hs
		882150 GSC_HUMAN (58-285): 5.34e-30: 116: 20.61		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Mm
		93658 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		E9Q6A7_MOUSE (95-233): 4.89e-20: 97.6: 27.08
+	Hs
		967857 PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00		BPTF_HUMAN (133-233): 1.15e-18: 93: 29.52
+	Mm
		101531 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		F8VQD1_MOUSE (92-345): 4.32e-15: 81.6: 14.61
+	Mm
		590421 PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15		PB1_MOUSE (92-345): 3.63e-15: 81.6: 14.61