HitPredict

Interactor 1: RIMS1 (Q86UR5)
Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1) (Rab-3-interacting protein 2)
Gene: RIMS1

Interactor 2: TNIK (Q9UKE5)
TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1692 Hs			1 1360
+	Hs
		324838 RIMS1_HUMAN (1-1692): 0: 972: 100.00		M4K4_HUMAN (1-1360): 0: 970: 59.11
+	Hs
		1200039 RIMS1_HUMAN (1-1692): 0: 972: 100.00		MRCKB_HUMAN (15-1330): 0: 661: 15.04
+	Mm
		949283 UN13A_MOUSE (756-1691): 1.05e-59: 229: 11.72		TNIK_MOUSE (1-1360): 0: 1208: 96.10
+	Mm
		93268 E9PXB7_MOUSE (863-1341): 1.02e-57: 218: 15.25		TNIK_MOUSE (1-1360): 0: 1208: 96.10
+	Hs
		647919 RIMS1_HUMAN (1-1692): 0: 972: 100.00		MARK3_HUMAN (3-675): 1.72e-124: 406: 16.37
+	Hs
		1356429 PCLO_HUMAN (1446-1666): 1.18e-29: 131: 21.37		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Mm
		808345 NEDD4_MOUSE (1510-1687): 1.31e-30: 133: 18.92		TNIK_MOUSE (1-1360): 0: 1208: 96.10
+	Mm
		949373 NED4L_MOUSE (1525-1687): 9.27e-28: 124: 20.71		TNIK_MOUSE (1-1360): 0: 1208: 96.10
+	Mm
		949403 RIMS1_MOUSE (192-869): 2.03e-17: 91.2: 13.95		TNIK_MOUSE (1-1360): 0: 1208: 96.10
+	Hs
		1233533 NED4L_HUMAN (1535-1687): 4.67e-28: 125: 21.12		MINK1_HUMAN (1-1360): 0: 1051: 60.43
+	Hs
		324819 SYT6_HUMAN (435-887): 1.53e-54: 201: 15.34		M4K4_HUMAN (1-1360): 0: 970: 59.11
+	Hs
		324844 SYT2_HUMAN (733-889): 2e-17: 88.8: 23.57		M4K4_HUMAN (1-1360): 0: 970: 59.11
+	Mm
		93277 E9PXB7_MOUSE (863-1341): 1.02e-57: 218: 15.25		TAOK2_MOUSE (1-858): 2.53e-132: 440: 22.14
+	Hs
		131575 SYT6_HUMAN (435-887): 1.53e-54: 201: 15.34		STK25_HUMAN (20-410): 8.77e-113: 362: 37.91
+	Hs
		566395 KPCA_HUMAN (1540-1659): 1.74e-12: 74.6: 31.15		KS6A2_HUMAN (10-709): 1.39e-140: 449: 18.52
+	Hs
		128938 P3C2A_HUMAN (1538-1664): 1.27e-23: 111: 27.48		STK24_HUMAN (20-340): 2.15e-111: 359: 43.03