Interactor 1: NOTC4 (P31695)
Neurogenic locus notch homolog protein 4 (Notch 4) [Cleaved into: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain]
Gene: Notch4

Interactor 2: EGFL7 (Q9QXT5)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 19503073
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF~EGF_CA, EGF_CA~EGF_CA
Common GO terms GO:0005112 - Notch binding
GO:0005509 - calcium ion binding
GO:0009986 - cell surface
GO:0045746 - negative regulation of Notch signaling pathway
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1964
Mm

1 275
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Last updated: 15 Jul 2024