HitPredict

Interactor 1: TF2B (P29052)
Transcription initiation factor IIB (General transcription factor TFIIB)
Gene: TfIIB

Interactor 2: TRF (Q27896)
TBP-related factor
Gene: TRF

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9335336
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	TBP~TFIIB
Common GO terms	GO:0005634 - nucleus GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0016251 - RNA polymerase II general transcription initiation factor activity
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 315 Dm			1 224
+	Hs
		589827 TF2B_HUMAN (1-315): 2.36e-141: 403: 79.11		TBP_HUMAN (29-224): 7.7e-97: 287: 56.57
+	Mm
		661496 TF2B_MOUSE (1-315): 2.33e-141: 403: 79.11		TBP_MOUSE (29-224): 5.81e-97: 286: 56.57
+	Dm
		661530 TF2B_DROME (1-315): 6.83e-148: 419: 100.00		Q8T052_DROME (1-223): 2.36e-82: 259: 32.74
+	Hs
		913420 TF2B_HUMAN (1-315): 2.36e-141: 403: 79.11		TBPL1_HUMAN (39-223): 6.54e-70: 213: 37.63
+	Sc
		526959 TF2B_YEAST (9-313): 5.14e-108: 319: 33.54		TBP_YEAST (6-223): 7.87e-99: 288: 48.89
+	Hs
		589904 TF3B_HUMAN (13-306): 1.75e-100: 310: 20.27		TBP_HUMAN (29-224): 7.7e-97: 287: 56.57
+	Dm
		1099962 Q9VEL2_DROME (14-303): 1.21e-90: 285: 22.45		TRF_DROME (1-224): 1.57e-102: 297: 100.00
+	Dm
		589972 Q9VEL2_DROME (14-303): 1.21e-90: 285: 22.45		TBP_DROME (22-223): 1.85e-98: 292: 55.39
+	Sc
		526960 TF3B_YEAST (11-304): 3.19e-86: 272: 23.26		TBP_YEAST (6-223): 7.87e-99: 288: 48.89
+	Sp
		571843 TF3B_SCHPO (14-304): 8.11e-85: 265: 20.68		TBP_SCHPO (16-223): 1.49e-95: 280: 53.37
+	Hs
		589923 BRF2_HUMAN (14-263): 2.59e-58: 194: 19.70		TBP_HUMAN (29-224): 7.7e-97: 287: 56.57
+	Pf
		905369 TF2B_PYRFU (9-300): 1.29e-98: 294: 31.88		TBP_PYRFU (46-131): 1.86e-22: 92.1: 36.05