HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.876

The method score is based on:

Property Details
Experiments 37071682, 17085597, 28514442, 23622247
Identification Methods cross-linking study, mass spectrometry studies of complexes, x-ray crystallography, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~14-3-3
Common GO terms GO:0004860 - protein kinase inhibitor activity
GO:0005737 - cytoplasm
GO:0005774 - vacuolar membrane
GO:0005829 - cytosol
GO:0005925 - focal adhesion
and 16 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 246
Hs

1 246
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+ At
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+ At
+ At
+ Sl
+ At
+ At
+ Mm
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
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+ Mm
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024