HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: TRI32 (Q13049)
E3 ubiquitin-protein ligase TRIM32 (EC 2.3.2.27) (72 kDa Tat-interacting protein) (RING-type E3 ubiquitin transferase TRIM32) (Tripartite motif-containing protein 32) (Zinc finger protein HT2A)
Gene: TRIM32

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	23444366, 24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 653
+	Hs
		909503 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00
+	Hs
		926989 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00
+	Mm
		910305 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		TRI32_MOUSE (7-653): 4.37e-160: 476: 95.53
+	Hs
		646853 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00
+	Mm
		933133 1433T_MOUSE (3-244): 9.37e-127: 360: 81.82		TRI32_MOUSE (7-653): 4.37e-160: 476: 95.53
+	Hs
		904508 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00
+	Hs
		981968 1433F_HUMAN (4-244): 2.7e-107: 311: 75.51		TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00
+	Hs
		684006 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		TRI32_HUMAN (1-653): 1.07e-169: 501: 100.00
+	Hs
		584921 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RO52_HUMAN (6-470): 1.76e-111: 345: 14.62
+	Hs
		584924 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		RO52_HUMAN (6-470): 1.76e-111: 345: 14.62
+	Hs
		909675 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		TRI68_HUMAN (8-490): 4.44e-106: 332: 13.89
+	Mm
		926891 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		TRIM3_MOUSE (1-645): 1.95e-104: 335: 16.50
+	Hs
		927496 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TRIM7_HUMAN (15-472): 1.17e-99: 316: 14.78
+	Hs
		584919 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		RO52_HUMAN (6-470): 1.76e-111: 345: 14.62
+	Hs
		647252 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		TRIM4_HUMAN (12-469): 3.42e-88: 285: 15.31
+	Hs
		684114 1433S_HUMAN (3-239): 3.38e-100: 293: 68.62		TRI68_HUMAN (8-490): 4.44e-106: 332: 13.89
+	Hs
		909495 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		TRI26_HUMAN (6-377): 1.71e-56: 202: 18.54
+	Hs
		927276 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		TRI59_HUMAN (11-336): 1.82e-56: 198: 21.35
+	Mm
		935544 1433F_MOUSE (4-244): 8.67e-108: 312: 75.51		TRI56_MOUSE (20-644): 1.12e-81: 274: 15.42
+	Hs
		647089 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		TRI59_HUMAN (11-336): 1.82e-56: 198: 21.35