HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	20598904
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 2472
+	Hs
		909544 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		927025 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Mm
		82753 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		B9EKJ1_MOUSE (1-2472): 0: 706: 98.18
+	Mm
		434798 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		SPTA1_MOUSE (1-2472): 2.17e-161: 558: 54.20
+	Mm
		926814 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		Q68FG2_MOUSE (141-1932): 3.76e-63: 242: 20.06
+	Hs
		297821 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		K0754_HUMAN (1-1482): 9.32e-58: 225: 14.65
+	Hs
		297815 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		K0754_HUMAN (1-1482): 9.32e-58: 225: 14.65
+	Hs
		297824 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		K0754_HUMAN (1-1482): 9.32e-58: 225: 14.65
+	Hs
		926931 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Mm
		926889 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		PLEC_MOUSE (1-1250): 7.03e-38: 159: 10.80
+	Hs
		909464 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		683282 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		926949 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		927068 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		PLEC_HUMAN (16-1253): 4.4e-31: 137: 9.18
+	Mm
		926806 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		SPTB2_MOUSE (1408-2420): 1.22e-29: 132: 18.86
+	Hs
		910159 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		683813 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		909975 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		CP250_HUMAN (1768-2439): 4.39e-10: 67.7: 8.94
+	Hs
		211554 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15
+	Hs
		211558 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15