HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1278
+	Hs
		909555 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		927035 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DCTN1_HUMAN (1-1278): 1.48e-90: 322: 100.00
+	Hs
		910062 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85
+	Hs
		683742 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		KI13B_HUMAN (14-145): 4.98e-32: 138: 32.85
+	Dm
		54781 1433E_DROME (3-245): 4.63e-144: 405: 64.90		A1ZA18_DROME (27-144): 1.15e-30: 134: 32.20
+	Hs
		522602 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH7_HUMAN (64-763): 2.65e-27: 122: 9.80
+	Hs
		725130 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH10_HUMAN (664-1275): 2.12e-23: 110: 10.13
+	Hs
		675148 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32
+	Mm
		926804 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH10_MOUSE (664-1275): 2.98e-22: 106: 10.29
+	Hs
		909658 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MRCKA_HUMAN (154-593): 9.15e-20: 98.4: 15.64
+	Hs
		683425 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MRCKA_HUMAN (154-593): 9.15e-20: 98.4: 15.64
+	Hs
		675151 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		CLIP1_HUMAN (111-828): 1.9e-21: 103: 11.32
+	Mm
		93548 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		DESP_MOUSE (177-1018): 4.44e-14: 80: 13.33
+	Mm
		926855 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		MYH9_MOUSE (826-1275): 8.37e-15: 82.2: 10.13
+	Hs
		724761 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH9_HUMAN (805-1271): 6.9e-15: 82.5: 11.54
+	Hs
		551660 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		DESP_HUMAN (227-1049): 1.36e-14: 81.5: 14.64
+	Hs
		728460 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYH11_HUMAN (49-439): 7.24e-12: 72.5: 9.16
+	Hs
		502907 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH3_HUMAN (830-1278): 8.46e-13: 75.6: 10.11
+	Hs
		728466 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		MYH11_HUMAN (49-439): 7.24e-12: 72.5: 9.16
+	Mm
		926895 1433Z_MOUSE (3-244): 3.14e-142: 399: 88.02		CLIP2_MOUSE (112-575): 7.46e-10: 65.7: 14.66