HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: Q5JSD8 (Q5JSD8)
Rho GTPase activating protein 21
Gene: ARHGAP21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 113
+	Hs
		909650 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RHG21_HUMAN (1-112): 1.02e-40: 144: 91.30
+	Hs
		683416 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RHG21_HUMAN (1-112): 1.02e-40: 144: 91.30
+	Hs
		64684 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RHG32_HUMAN (2-112): 9.38e-39: 139: 25.44
+	Hs
		64662 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		RHG32_HUMAN (2-112): 9.38e-39: 139: 25.44
+	Mm
		910284 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		RHG33_MOUSE (2-112): 4.76e-38: 137: 27.19
+	Hs
		909743 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SRGP1_HUMAN (2-106): 3.14e-37: 134: 29.52
+	Hs
		70666 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		MYO9A_HUMAN (2-112): 2.7e-36: 132: 26.32
+	Hs
		70650 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		MYO9A_HUMAN (2-112): 2.7e-36: 132: 26.32
+	Mm
		910285 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		SRGP3_MOUSE (2-106): 3.74e-36: 131: 30.48
+	Mm
		910322 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		SRGP2_MOUSE (2-105): 3.13e-36: 131: 28.85
+	Hs
		910011 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		RGAP1_HUMAN (2-113): 8.65e-36: 130: 30.44
+	Hs
		253335 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SRGP2_HUMAN (2-112): 1.24e-35: 129: 27.03
+	Hs
		253321 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SRGP2_HUMAN (2-112): 1.24e-35: 129: 27.03
+	Hs
		909637 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		Q5JSD8_HUMAN (1-113): 2.6e-39: 128: 100.00
+	Hs
		909718 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SYDE1_HUMAN (2-95): 1.62e-34: 126: 32.98
+	Hs
		683476 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SYDE1_HUMAN (2-95): 1.62e-34: 126: 32.98
+	Hs
		909659 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		SYDE2_HUMAN (2-112): 5.47e-34: 125: 22.58
+	Hs
		506563 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		BCR_HUMAN (2-111): 1.52e-33: 124: 34.51
+	Hs
		683426 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		SYDE2_HUMAN (2-112): 5.47e-34: 125: 22.58
+	Hs
		506525 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		BCR_HUMAN (2-111): 1.52e-33: 124: 34.51