HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: E41L3 (Q9Y2J2)
Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]
Gene: EPB41L3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.739

Property	Details
Experiments	24366813, 11996670, 17353931, 36931259, 15324660, 24255178
Identification Methods	affinity chromatography technology, two hybrid, pull down, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1087
+	Hs
		910185 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L3_HUMAN (1-1087): 0: 752: 100.00
+	Hs
		663970 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN4_HUMAN (91-695): 1.96e-140: 448: 29.55
+	Hs
		663962 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN4_HUMAN (91-695): 1.96e-140: 448: 29.55
+	Hs
		909498 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN13_HUMAN (4-988): 4.66e-130: 440: 16.62
+	Hs
		683305 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN13_HUMAN (4-988): 4.66e-130: 440: 16.62
+	Hs
		683735 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L5_HUMAN (74-826): 2.96e-137: 433: 25.07
+	Mm
		910323 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		FRM4B_MOUSE (100-945): 1.46e-125: 411: 15.72
+	Hs
		640229 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN3_HUMAN (90-701): 3.39e-122: 399: 23.67
+	Hs
		640216 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN3_HUMAN (90-701): 3.39e-122: 399: 23.67
+	Hs
		909595 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN14_HUMAN (91-1077): 1.78e-119: 398: 15.41
+	Hs
		683372 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN14_HUMAN (91-1077): 1.78e-119: 398: 15.41
+	Hs
		683499 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		FRMD5_HUMAN (108-582): 2.15e-124: 394: 29.73
+	Hs
		909614 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		PTN21_HUMAN (91-1043): 1.1e-117: 393: 18.61
+	Hs
		683381 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		PTN21_HUMAN (91-1043): 1.1e-117: 393: 18.61
+	Hs
		204644 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L2_HUMAN (583-1087): 1.39e-44: 177: 32.64
+	Hs
		204620 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L2_HUMAN (583-1087): 1.39e-44: 177: 32.64
+	Hs
		204648 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		E41L2_HUMAN (583-1087): 1.39e-44: 177: 32.64
+	Hs
		505612 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		EPB41_HUMAN (701-1083): 3.49e-41: 166: 33.33
+	Hs
		910025 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		E41L1_HUMAN (631-1084): 9.44e-23: 107: 21.33
+	Hs
		683710 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		E41L1_HUMAN (631-1084): 9.44e-23: 107: 21.33