HitPredict

Interactor 1: RUXGL (A8MWD9)
Putative small nuclear ribonucleoprotein G-like protein 15
Gene: SNRPGP15

Interactor 2: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LSM~U1snRNP70_N
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005685 - U1 snRNP GO:0071004 - U2-type prespliceosome GO:0071011 - precatalytic spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 76 Hs			1 437
+	Hs
		912052 RUXG_HUMAN (1-76): 5.34e-30: 102: 94.74		U1SBP_HUMAN (83-301): 7.9e-48: 166: 40.46
+	Hs
		442013 RUXG_HUMAN (1-76): 5.34e-30: 102: 94.74		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Dm
		565307 RUXF_DROME (1-74): 2.2e-24: 88.6: 28.38		RU17_DROME (1-212): 1.83e-50: 178: 68.40
+	Hs
		68425 RUXGL_HUMAN (1-76): 3.09e-29: 100: 100.00		U1SBP_HUMAN (83-301): 7.9e-48: 166: 40.46
+	Sp
		143345 RUXG_SCHPO (1-76): 6.57e-25: 89.4: 47.37		RU17_SCHPO (1-277): 2.14e-51: 175: 38.27
+	Sp
		143344 RUXF_SCHPO (1-72): 1.39e-23: 86.3: 24.00		RU17_SCHPO (1-277): 2.14e-51: 175: 38.27
+	Hs
		927963 RSMN_HUMAN (1-70): 9.31e-23: 88.6: 21.25		U1SBP_HUMAN (83-301): 7.9e-48: 166: 40.46
+	Hs
		442037 RSMN_HUMAN (1-70): 9.31e-23: 88.6: 21.25		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		911852 RUXF_HUMAN (5-73): 9.05e-24: 87.1: 26.09		U1SBP_HUMAN (83-301): 7.9e-48: 166: 40.46
+	Hs
		538978 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		U1SBP_HUMAN (83-301): 7.9e-48: 166: 40.46
+	Hs
		442012 RUXF_HUMAN (5-73): 9.05e-24: 87.1: 26.09		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Hs
		441858 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		RU17_HUMAN (1-437): 8.99e-46: 165: 100.00
+	Sc
		770323 RUXG_YEAST (7-76): 5.33e-22: 82.3: 50.69		RU17_YEAST (3-297): 9.1e-46: 162: 26.58
+	Sc
		873653 RUXF_YEAST (5-73): 2.81e-21: 80.6: 24.29		RU17_YEAST (3-297): 9.1e-46: 162: 26.58
+	Sc
		376834 LSM1_YEAST (3-74): 3.52e-22: 85.6: 27.27		PABP_YEAST (2-281): 3.47e-29: 121: 12.15
+	Sc
		376892 RUXF_YEAST (5-73): 2.81e-21: 80.6: 24.29		PABP_YEAST (2-281): 3.47e-29: 121: 12.15
+	Mm
		646096 RSMB_MOUSE (1-70): 6.51e-22: 85.9: 21.25		TIA1_MOUSE (3-246): 4.89e-27: 113: 13.42
+	Hs
		538845 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		CSTF2_HUMAN (85-177): 1.23e-20: 96.4: 32.26
+	Hs
		235785 RUXF_HUMAN (5-73): 9.05e-24: 87.1: 26.09		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55
+	Hs
		235690 RSMB_HUMAN (1-70): 5.01e-22: 86.7: 21.25		HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55