HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0045296 - cadherin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 7388
+	Hs
		910159 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		MACF1_HUMAN (1-7388): 0: 2387: 100.00
+	Hs
		927659 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		MACF1_HUMAN (1-7388): 0: 2387: 100.00
+	Hs
		684048 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Mm
		93548 1433E_MOUSE (2-246): 4.41e-146: 410: 60.41		DESP_MOUSE (2737-3805): 1.11e-27: 127: 8.89
+	Hs
		683978 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Mm
		926889 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		PLEC_MOUSE (5698-7245): 3.41e-29: 132: 9.08
+	Hs
		684024 1433S_HUMAN (1-248): 3.48e-158: 440: 100.00		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		551660 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		927068 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		909464 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		297821 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		K0754_HUMAN (757-1741): 1.73e-10: 70.9: 10.05
+	Hs
		909544 1433E_HUMAN (2-246): 4.41e-146: 410: 60.41		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Hs
		926965 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		ACTN3_HUMAN (5633-6111): 4.77e-17: 92.1: 12.20
+	Hs
		926949 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Mm
		926806 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		SPTB2_MOUSE (6378-7134): 3.94e-11: 72.8: 13.67
+	Hs
		926931 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Mm
		926814 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		Q68FG2_MOUSE (330-850): 2.48e-10: 70.5: 12.57
+	Hs
		297824 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		K0754_HUMAN (757-1741): 1.73e-10: 70.9: 10.05
+	Hs
		927025 1433Z_HUMAN (1-243): 5.4e-136: 384: 70.37		SPTN1_HUMAN (433-1344): 7.43e-10: 68.8: 13.39
+	Mm
		82753 1433Z_MOUSE (1-243): 1.34e-136: 385: 69.96		B9EKJ1_MOUSE (433-1344): 4.47e-09: 66.1: 13.69