HitPredict

Interactor 1: PAX6 (P26367)
Paired box protein Pax-6 (Aniridia type II protein) (Oculorhombin)
Gene: PAX6

Interactor 2: RCOR3 (Q9P2K3)
REST corepressor 3
Gene: RCOR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 422 Hs			1 495
+	Hs
		662290 PAX7_HUMAN (4-417): 1.32e-82: 264: 35.81		RCOR3_HUMAN (1-495): 5.58e-139: 411: 100.00
+	Hs
		662295 PAX7_HUMAN (4-417): 1.32e-82: 264: 35.81		RCOR1_HUMAN (1-384): 4.08e-96: 300: 63.47
+	Hs
		278243 PAX6_HUMAN (1-422): 2.15e-115: 345: 100.00		NCOR1_HUMAN (35-484): 3.12e-50: 187: 17.04
+	Hs
		685400 PAX6_HUMAN (1-422): 2.15e-115: 345: 100.00		NCOR2_HUMAN (35-478): 2.11e-43: 166: 18.02
+	Hs
		278237 PAX7_HUMAN (4-417): 1.32e-82: 264: 35.81		NCOR1_HUMAN (35-484): 3.12e-50: 187: 17.04
+	Hs
		662304 PAX7_HUMAN (4-417): 1.32e-82: 264: 35.81		NCOR2_HUMAN (35-478): 2.11e-43: 166: 18.02
+	Mm
		1038080 PAX5_MOUSE (1-372): 5.5e-68: 222: 34.32		NCOR1_MOUSE (35-479): 2.5e-53: 196: 18.65
+	Hs
		278315 PAX8_HUMAN (1-418): 7.81e-64: 213: 32.08		NCOR1_HUMAN (35-484): 3.12e-50: 187: 17.04
+	Hs
		1040095 PAX2_HUMAN (1-364): 1.06e-67: 222: 35.71		NCOR2_HUMAN (35-478): 2.11e-43: 166: 18.02
+	Hs
		1056665 PAX8_HUMAN (1-418): 7.81e-64: 213: 32.08		NCOR2_HUMAN (35-478): 2.11e-43: 166: 18.02
+	Hs
		278286 PAX9_HUMAN (1-196): 1.62e-45: 162: 47.96		NCOR1_HUMAN (35-484): 3.12e-50: 187: 17.04
+	Hs
		938523 PAX9_HUMAN (1-196): 1.62e-45: 162: 47.96		NCOR2_HUMAN (35-478): 2.11e-43: 166: 18.02