Interactor 1: ICAL (P27321)
Calpastatin (Calpain inhibitor)
Gene: Cast
Interactor 2: CAN2 (Q07009)
Calpain-2 catalytic subunit (EC 3.4.22.53) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain)
Gene: Capn2
Species: Rattus norvegicus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.41 | 1.00 | 0.647 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17543955 |
| Identification Methods | surface plasmon resonance |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Calpain_III~Calpain_inhib, Calpain_inhib~EF-hand_8, Calpain_inhib~Peptidase_C2 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007520 - myoblast fusion GO:0030163 - protein catabolic process |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
