Protein: IZUM1
Izumo sperm-egg fusion protein 1 (Oocyte binding/fusion factor) (OBF) (Sperm-specific protein izumo)

Gene: IZUM1, IZUMO1
Organism: Homo sapiens
Interactions: 32
UniProt ID: Q8IYV9

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0002080 - acrosomal membrane
GO:0005102 - signaling receptor binding
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

61960

JUNO
Sperm-egg fusion protein Juno

2

0

Small-scale

0.798

High

1223687

IZUM1
Izumo sperm-egg fusion protein 1

1

0

Small-scale

0.657

High

616994

PTPRD
Receptor-type tyrosine-protein phosphatase delta

2

1

High-throughput

0.628

High

1172512

AN13D
Ankyrin repeat domain-containing protein 13D

2

1

High-throughput

0.628

High

1223688

AN13A
Ankyrin repeat domain-containing protein 13A

2

1

High-throughput

0.628

High

1223702

CNOT6
CCR4-NOT transcription complex subunit 6

2

1

High-throughput

0.611

High

229556

ADCY3
Adenylate cyclase type 3

2

0

High-throughput

0.602

High

1044924

AVR2B
Activin receptor type-2B

2

0

High-throughput

0.602

High

1223689

S39AB
Zinc transporter ZIP11

2

0

High-throughput

0.602

High

1223693

CNOT9
CCR4-NOT transcription complex subunit 9

2

0

High-throughput

0.602

High

1223694

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

2

0

High-throughput

0.602

High

1223695

LRAT2
Protein LRATD2

2

0

High-throughput

0.602

High

1223697

EFC4B
EF-hand calcium-binding domain-containing protein 4B

2

0

High-throughput

0.602

High

1223699

GHITM
Growth hormone-inducible transmembrane protein

2

0

High-throughput

0.602

High

1223703

S4A7
Sodium bicarbonate cotransporter 3

2

0

High-throughput

0.602

High

489987

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

1

High-throughput

0.536

High

994658

DDR1
Epithelial discoidin domain-containing receptor 1

1

2

High-throughput

0.536

High

61409

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.513

High

508093

FGFR1
Fibroblast growth factor receptor 1

1

0

High-throughput

0.513

High

523054

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.513

High

1045032

AT1A4
Sodium/potassium-transporting ATPase subunit alpha-4

1

0

High-throughput

0.513

High

1152569

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

1

0

High-throughput

0.513

High

1223690

XXLT1
Xyloside xylosyltransferase 1

1

0

High-throughput

0.513

High

1223692

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.513

High

1223700

TMX1
Thioredoxin-related transmembrane protein 1

1

0

High-throughput

0.513

High

90004

D6R9H6
CCR4-NOT transcription complex subunit 6

1

1

High-throughput

0.407

High

1022939

CDC16
Cell division cycle protein 16 homolog

2

0

High-throughput

0.328

High

1223701

CNO11
CCR4-NOT transcription complex subunit 11

2

0

High-throughput

0.328

High

1223691

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.279

Low

1223698

NFIP1
NEDD4 family-interacting protein 1

1

0

High-throughput

0.279

Low

1223696

VRK1
Serine/threonine-protein kinase VRK1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024