HitPredict

Interactor 1: HOG1 (P32485)
Mitogen-activated protein kinase HOG1 (MAP kinase HOG1) (EC 2.7.11.24) (High osmolarity glycerol response protein 1)
Gene: HOG1

Interactor 2: NUP2 (P32499)
Nucleoporin NUP2 (Nuclear pore protein NUP2) (p95)
Gene: NUP2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.664

Property	Details
Experiments	23645671, 29738528, 31208443
Identification Methods	affinity chromatography technology, enzymatic study, proximity labelling technology
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 435 Sc			1 720
+	Sc
		595003 HOG1_YEAST (1-435): 2.33e-166: 476: 100.00		NUP1_YEAST (223-591): 1.07e-12: 73.8: 21.72
+	Sc
		541853 HOG1_YEAST (1-435): 2.33e-166: 476: 100.00		NSP1_YEAST (159-520): 1.2e-11: 70.1: 22.37
+	Hs
		647517 MK03_HUMAN (12-345): 2.48e-144: 418: 46.51		NU153_HUMAN (184-601): 2.05e-21: 102: 18.00
+	Hs
		834605 MK14_HUMAN (3-352): 7.57e-141: 408: 50.42		NU153_HUMAN (184-601): 2.05e-21: 102: 18.00
+	Ce
		1088944 PMK1_CAEEL (2-348): 7.75e-143: 414: 46.88		Q21021_CAEEL (492-720): 4.23e-18: 91.1: 16.88
+	Hs
		658853 MK01_HUMAN (10-349): 2.98e-138: 401: 46.86		NU153_HUMAN (184-601): 2.05e-21: 102: 18.00
+	Ce
		1088947 PMK1_CAEEL (2-348): 7.75e-143: 414: 46.88		Q86G90_CAEEL (492-720): 2.11e-14: 79.2: 15.29
+	Ce
		764305 MPK1_CAEEL (11-345): 2e-103: 316: 47.25		Q21021_CAEEL (492-720): 4.23e-18: 91.1: 16.88
+	Ce
		764320 MPK1_CAEEL (11-345): 2e-103: 316: 47.25		Q86G90_CAEEL (492-720): 2.11e-14: 79.2: 15.29