Protein: PDE7A
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A (EC 3.1.4.53) (HCP1) (TM22) (cAMP-specific phosphodiesterase 7A)

Gene: PDE7A
Organism: Homo sapiens
Interactions: 19
UniProt ID: Q13946

Gene Ontology (top 5):
GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005829 - cytosol
GO:0006198 - cAMP catabolic process
GO:0019933 - cAMP-mediated signaling
GO:0046872 - metal ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

605674

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

3

11

High-throughput

0.667

High

1119430

UBX11
UBX domain-containing protein 11

3

0

High-throughput

0.638

High

729820

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.601

High

1119435

VP13A
Intermembrane lipid transfer protein VPS13A

2

0

High-throughput

0.585

High

943762

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

1

1

High-throughput

0.541

High

124775

AIP
AH receptor-interacting protein

1

7

High-throughput

0.536

High

603266

KPCA
Protein kinase C alpha type

1

5

High-throughput

0.536

High

971509

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

990206

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.536

High

1119431

DCAF8
DDB1- and CUL4-associated factor 8

1

4

High-throughput

0.536

High

701980

TMOD1
Tropomodulin-1

1

0

High-throughput

0.513

High

1119436

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.513

High

880139

PTH2R
Parathyroid hormone 2 receptor

1

1

High-throughput

0.489

High

1119433

CYTSA
Cytospin-A

1

1

High-throughput

0.489

High

1119432

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.445

High

1119434

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

1

High-throughput

0.407

High

888455

TSP3
Thrombospondin-3

3

0

High-throughput

0.347

High

702184

LYOX
Protein-lysine 6-oxidase

1

0

High-throughput

0.279

Low

511034

PNM6A
Paraneoplastic antigen-like protein 6A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025