HitPredict

Interactor 1: RPN2 (P32565)
26S proteasome regulatory subunit RPN2
Gene: RPN2

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.737

The method score is based on:

Property Details
Experiments 16554755, 36621624, 23900548, 37968396, 22237024, 22307589, 22940862
Identification Methods affinity chromatography technology, x-ray crystallography, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0008540 - proteasome regulatory particle, base subcomplex
GO:0031625 - ubiquitin protein ligase binding
GO:0034515 - proteasome storage granule
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 945
Sc

1 405
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Dm
+ Hs
+ Sp
+ Dm
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024