HitPredict

Interactor 1: A8K287 (A8K287)
Synaptosomal-associated protein
Gene: SNAP23

Interactor 2: STX11 (O75558)
Syntaxin-11
Gene: STX11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Hs			1 287
+	Hs
		124030 SNP23_HUMAN (1-211): 1.07e-71: 218: 100.00		STX1B_HUMAN (1-286): 1.33e-71: 223: 32.17
+	Hs
		124057 SNP23_HUMAN (1-211): 1.07e-71: 218: 100.00		STX1A_HUMAN (1-286): 2.83e-70: 220: 28.67
+	Rn
		266931 SNP23_RAT (1-211): 6.21e-69: 211: 87.20		STX1B_RAT (1-286): 1.33e-71: 223: 32.17
+	Hs
		123997 SNP23_HUMAN (1-211): 1.07e-71: 218: 100.00		STX2_HUMAN (1-286): 7.66e-68: 214: 31.82
+	Mm
		148586 SNP23_MOUSE (1-211): 2.56e-68: 209: 87.20		STX1A_MOUSE (1-286): 2.39e-71: 223: 28.67
+	Hs
		123952 SNP23_HUMAN (1-211): 1.07e-71: 218: 100.00		STX11_HUMAN (1-287): 1.26e-63: 203: 100.00
+	Hs
		124045 SNP23_HUMAN (1-211): 1.07e-71: 218: 100.00		STX4_HUMAN (1-286): 1.55e-58: 190: 27.53
+	Dm
		1174541 Q9VH76_DROME (6-211): 4.49e-61: 191: 47.57		STX1A_DROME (10-286): 7.21e-68: 214: 26.72
+	Hs
		124048 SNP23_HUMAN (1-211): 1.07e-71: 218: 100.00		STX3_HUMAN (1-276): 4.4e-55: 181: 30.44
+	Rn
		266935 SNP23_RAT (1-211): 6.21e-69: 211: 87.20		STX4_RAT (1-286): 3.8e-55: 182: 26.48
+	Rn
		266934 SNP23_RAT (1-211): 6.21e-69: 211: 87.20		STX3_RAT (1-276): 7.7e-54: 178: 29.71
+	Mm
		148590 SNP23_MOUSE (1-211): 2.56e-68: 209: 87.20		STX3_MOUSE (1-276): 1.38e-53: 177: 29.71
+	At
		1456079 SNP33_ARATH (1-210): 2.43e-60: 192: 22.54		SY121_ARATH (17-278): 3.41e-54: 181: 18.59
+	Hs
		123944 SNP23_HUMAN (1-211): 1.07e-71: 218: 100.00		STX7_HUMAN (56-275): 1.01e-44: 154: 15.25
+	Hs
		124070 SNP23_HUMAN (1-211): 1.07e-71: 218: 100.00		STX12_HUMAN (47-283): 7.54e-44: 152: 19.09
+	Hs
		124075 SNP23_HUMAN (1-211): 1.07e-71: 218: 100.00		STX19_HUMAN (1-278): 6.72e-42: 147: 35.92
+	At
		1192495 SNP33_ARATH (1-210): 2.43e-60: 192: 22.54		SY111_ARATH (1-278): 1.36e-47: 162: 17.25
+	Dm
		1174441 Q9VH76_DROME (6-211): 4.49e-61: 191: 47.57		STX5_DROME (2-280): 2.26e-43: 155: 12.08
+	Dm
		1475584 Q9VH76_DROME (6-211): 4.49e-61: 191: 47.57		Q9VR90_DROME (10-284): 1.81e-43: 153: 13.37
+	Dm
		1270183 Q9VH76_DROME (6-211): 4.49e-61: 191: 47.57		STX4_DROME (28-279): 4.63e-43: 151: 17.86