HitPredict

Interactor 1: A0A087WW66 (A0A087WW66)
26S proteasome non-ATPase regulatory subunit 1
Gene: PSMD1

Interactor 2: PSB2 (P49721)
Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I)
Gene: PSMB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 914 Hs			1 201
+	Hs
		691 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB5_HUMAN (2-197): 1.96e-66: 206: 17.86
+	Hs
		688 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSA4_HUMAN (3-198): 5.76e-65: 202: 17.73
+	Hs
		710 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB7_HUMAN (3-199): 1.32e-64: 202: 19.80
+	Hs
		686 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86
+	Hs
		656760 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB5_HUMAN (2-197): 1.96e-66: 206: 17.86
+	Hs
		1303479 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB7_HUMAN (3-199): 1.32e-64: 202: 19.80
+	Hs
		638180 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA4_HUMAN (3-198): 5.76e-65: 202: 17.73
+	Hs
		684 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB1_HUMAN (3-198): 2.07e-57: 182: 23.42
+	Hs
		637734 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA2_HUMAN (4-197): 1.04e-64: 201: 17.86
+	Hs
		832152 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB2_HUMAN (1-201): 5.46e-65: 200: 100.00
+	Hs
		594615 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB1_HUMAN (3-198): 2.07e-57: 182: 23.42
+	Hs
		690 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB6_HUMAN (3-188): 2.95e-44: 148: 17.74
+	Hs
		656638 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB6_HUMAN (3-188): 2.95e-44: 148: 17.74
+	Dm
		1178951 PSMD1_DROME (2-894): 0: 1056: 58.84		Q7K148_DROME (2-198): 6.07e-66: 205: 22.34
+	Dm
		1359010 PSMD1_DROME (2-894): 0: 1056: 58.84		Q9VJJ0_DROME (1-195): 3.77e-66: 203: 51.28
+	Dm
		1359016 PSMD1_DROME (2-894): 0: 1056: 58.84		Q9VUJ1_DROME (4-199): 3.12e-64: 201: 19.90
+	Dm
		771308 PSMD1_DROME (2-894): 0: 1056: 58.84		PSA2_DROME (4-197): 4.6e-64: 199: 18.88
+	Sc
		604769 RPN2_YEAST (2-914): 0: 919: 38.04		PSB4_YEAST (1-193): 1.25e-78: 235: 44.85
+	Sc
		675399 RPN2_YEAST (2-914): 0: 919: 38.04		PSB5_YEAST (2-198): 7.84e-67: 208: 17.77
+	Sc
		625919 RPN2_YEAST (2-914): 0: 919: 38.04		PSB2_YEAST (3-184): 1.28e-46: 155: 17.03