Interactor 1: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Interactor 2: RPN8 (Q08723)
26S proteasome regulatory subunit RPN8
Gene: RPN8

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 9584156, 16554755, 16429126, 37968396, 31848235, 22237024, 22940862, 14759368, 19446323
Identification Methods biochemical, affinity chromatography technology, cross-linking study, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains JAB~PC_rep
Common GO terms GO:0000502 - proteasome complex
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0034515 - proteasome storage granule
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 993
Sc

1 338
+ Hs
+ At
+ At
+ Sp
+ Hs
+ At
+ Sp
+ Dm
+ Hs
+ Dm
+ Hs
+ Dm
+ Sc
+ Dm
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 11Aug2025