HitPredict

Interactor 1: ESPN (B1AK53)
Espin (Autosomal recessive deafness type 36 protein) (Ectoplasmic specialization protein)
Gene: ESPN

Interactor 2: ITM2B (Q9Y287)
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Protein E25B) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]
Gene: ITM2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	34446781
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 854 Hs			1 266
+	Hs
		1356875 KDIS_HUMAN (3-349): 3.59e-86: 303: 23.08		ITM2B_HUMAN (1-266): 1.45e-148: 417: 100.00
+	Rn
		251024 ANK3_RAT (1-86): 2.22e-14: 80.1: 19.77		ITM2B_RAT (1-266): 5.07e-151: 423: 96.24
+	Hs
		1021476 ANK3_HUMAN (1-86): 9.02e-14: 78.2: 19.77		ITM2B_HUMAN (1-266): 1.45e-148: 417: 100.00