HitPredict

Interactor 1: SLA1 (P32790)
Actin cytoskeleton-regulatory complex protein SLA1
Gene: SLA1

Interactor 2: AP18B (P53309)
Clathrin coat assembly protein AP180B
Gene: YAP1802

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	34887356, 32400111
Identification Methods	protein complementation assay, fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0005935 - cellular bud neck GO:0006897 - endocytosis
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1244 Sc			1 568
+	Sc
		697924 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		AP18A_YEAST (3-558): 4.03e-111: 346: 44.33
+	Sc
		697894 SLA1_YEAST (1-1244): 7.36e-166: 528: 100.00		SLA2_YEAST (1-349): 3.36e-71: 247: 13.09
+	Hs
		1036476 WNK1_HUMAN (715-1108): 1.54e-33: 143: 13.73		PICAL_HUMAN (3-557): 9.13e-119: 367: 18.66
+	Sc
		692238 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		AP18B_YEAST (1-568): 8.21e-139: 416: 100.00
+	Sc
		692225 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		AP18A_YEAST (3-558): 4.03e-111: 346: 44.33
+	Sc
		692213 PAN1_YEAST (713-1210): 5.38e-11: 69.7: 16.79		SLA2_YEAST (1-349): 3.36e-71: 247: 13.09
+	Dm
		113976 M9PB30_DROME (125-851): 1.04e-16: 88.8: 7.50		M9PB30_DROME (366-566): 3.66e-15: 81.5: 9.61
+	Mm
		1351630 PCLO_MOUSE (151-1049): 1.74e-16: 88: 8.79		PCLO_MOUSE (244-567): 6.24e-11: 67.7: 11.48
+	Mm
		99853 F6M2J9_MOUSE (373-1096): 1.55e-16: 87.6: 7.46		F8WI37_MOUSE (240-565): 2.95e-09: 62.3: 9.01
+	Mm
		1207212 NCOA6_MOUSE (138-1240): 9.17e-12: 72.2: 6.90		KMT2C_MOUSE (240-565): 2.95e-09: 62.3: 9.01