HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: TMPS3 (P57727)
Transmembrane protease serine 3 (EC 3.4.21.-) (Serine protease TADG-12) (Tumor-associated differentially-expressed gene 12 protein)
Gene: TMPRSS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 592 Hs			1 454
+	Hs
		699078 CALX_HUMAN (1-592): 0: 786: 100.00		TMPSD_HUMAN (20-449): 2.03e-121: 367: 35.28
+	Hs
		698829 CALX_HUMAN (1-592): 0: 786: 100.00		TM11B_HUMAN (45-449): 3.92e-111: 335: 29.52
+	Hs
		366535 CALX_HUMAN (1-592): 0: 786: 100.00		TPA_HUMAN (30-449): 6.35e-98: 306: 23.06
+	Hs
		437628 CALX_HUMAN (1-592): 0: 786: 100.00		HEPS_HUMAN (119-454): 2.05e-99: 305: 37.18
+	Hs
		699307 CALX_HUMAN (1-592): 0: 786: 100.00		TEST_HUMAN (204-451): 1.99e-99: 301: 37.93
+	Hs
		170558 CLGN_HUMAN (11-546): 0: 652: 59.85		TMPS2_HUMAN (28-451): 7.15e-116: 350: 42.17
+	Hs
		170845 CLGN_HUMAN (11-546): 0: 652: 59.85		TM11B_HUMAN (45-449): 3.92e-111: 335: 29.52
+	Hs
		170983 CLGN_HUMAN (11-546): 0: 652: 59.85		TMPS4_HUMAN (76-452): 4.08e-109: 331: 35.12
+	Hs
		170603 CLGN_HUMAN (11-546): 0: 652: 59.85		TPA_HUMAN (30-449): 6.35e-98: 306: 23.06
+	Hs
		170960 CLGN_HUMAN (11-546): 0: 652: 59.85		TMPS5_HUMAN (98-452): 7.19e-98: 303: 38.48
+	Hs
		188819 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		TMPS2_HUMAN (28-451): 7.15e-116: 350: 42.17
+	Hs
		697938 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		TM11B_HUMAN (45-449): 3.92e-111: 335: 29.52
+	Hs
		366534 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		TPA_HUMAN (30-449): 6.35e-98: 306: 23.06