HitPredict

Interactor 1: PSA5 (P28066)
Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome subunit alpha-5) (alpha-5) (Proteasome zeta chain)
Gene: PSMA5

Interactor 2: PSMF1 (Q92530)
Proteasome inhibitor PI31 subunit (hPI31)
Gene: PSMF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	33961781, 35271311, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PI31_Prot_C~Proteasome
Common GO terms	GO:0005829 - cytosol GO:0005839 - proteasome core complex GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 241 Hs			1 271
+	Hs
		165385 PSA7_HUMAN (8-239): 5.33e-89: 265: 36.17		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		680969 PSA1_HUMAN (3-241): 7.76e-89: 265: 28.81		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		681206 PSA2_HUMAN (3-241): 2.39e-89: 265: 30.96		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		954868 PSA6_HUMAN (4-241): 1.52e-88: 263: 25.93		PSMF1_HUMAN (1-271): 3.21e-157: 439: 100.00
+	Hs
		954826 PSA6_HUMAN (4-241): 1.52e-88: 263: 25.93		Q5QPM9_HUMAN (1-183): 1.98e-104: 302: 100.00