HitPredict

Interactor 1: TEAD1 (P28347)
Transcriptional enhancer factor TEF-1 (NTEF-1) (Protein GT-IIC) (TEA domain family member 1) (TEAD-1) (Transcription factor 13) (TCF-13)
Gene: TEAD1

Interactor 2: CIC (Q96RK0)
Protein capicua homolog
Gene: CIC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29844126, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 2517
+	Hs
		703108 TEAD1_HUMAN (1-426): 0: 782: 100.00		SOX2_HUMAN (1073-1308): 2.24e-57: 204: 24.05
+	Mm
		717012 TEAD1_MOUSE (1-426): 0: 783: 99.30		Q60I23_MOUSE (1102-1308): 2.16e-56: 201: 27.40
+	Hs
		703222 TEAD1_HUMAN (1-426): 0: 782: 100.00		NCOR2_HUMAN (294-2060): 9.59e-17: 89.9: 10.04
+	Hs
		703171 TEAD1_HUMAN (1-426): 0: 782: 100.00		KMT2C_HUMAN (1133-2516): 1.63e-13: 79.5: 8.66