HitPredict

Interactor 1: NCKP1 (P28660)
Nck-associated protein 1 (NAP 1) (Brain protein H19) (MH19) (Membrane-associated protein HEM-2) (p125Nap1)
Gene: Nckap1

Interactor 2: CYFP2 (Q5SQX6)
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)
Gene: Cyfip2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28671696, 32560809
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CYRIA-B_Rac1-bd~Nckap1, FragX_IP~Nckap1
Common GO terms	GO:0031209 - SCAR complex GO:0031267 - small GTPase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1128 Mm			1 1253
+	Hs
		1390228 NCKP1_HUMAN (1-1128): 0: 1693: 99.38		CYFP2_HUMAN (1-1253): 0: 2126: 97.97
+	Hs
		1272227 NCKP1_HUMAN (1-1128): 0: 1693: 99.38		CYFP1_HUMAN (1-1252): 0: 2048: 87.55
+	Mm
		704288 NCKP1_MOUSE (1-1128): 0: 1695: 100.00		CYFP1_MOUSE (1-1252): 0: 2041: 87.31
+	Dm
		936253 HEM_DROME (1-1122): 0: 1546: 59.66		CYFIP_DROME (1-1252): 0: 1908: 66.02
+	Ce
		233350 GEX3_CAEEL (8-1121): 0: 1355: 40.52		CYFIP_CAEEL (1-1251): 0: 1759: 51.50
+	At
		1209897 NCKP1_ARATH (70-1126): 0: 1083: 21.54		PIR_ARATH (5-1239): 0: 1513: 28.94