HitPredict

Interactor 1: S10A2 (P29034)
Protein S100-A2 (CAN19) (Protein S-100L) (S100 calcium-binding protein A2)
Gene: S100A2

Interactor 2: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.51	0.50	0.506

Property	Details
Experiments	20591429
Identification Methods	pull down, molecular sieving, surface plasmon resonance
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 98 Hs			1 491
+	Hs
		657028 S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		686803 S10A4_HUMAN (2-97): 3.37e-38: 124: 61.46		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		1028270 HORN_HUMAN (2-90): 4.04e-32: 119: 28.09		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		407612 S100B_HUMAN (4-92): 9.17e-33: 111: 44.94		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		445165 S10A6_HUMAN (2-93): 2.21e-30: 104: 46.74		MDM2_HUMAN (1-491): 0: 710: 100.00
+	Hs
		179675 S10A2_HUMAN (1-98): 3.29e-39: 127: 100.00		MDM4_HUMAN (4-489): 0: 531: 32.08
+	Hs
		179673 S10A1_HUMAN (2-91): 3.93e-38: 124: 52.22		MDM4_HUMAN (4-489): 0: 531: 32.08
+	Hs
		179659 S100B_HUMAN (4-92): 9.17e-33: 111: 44.94		MDM4_HUMAN (4-489): 0: 531: 32.08
+	Hs
		179679 S10A5_HUMAN (2-91): 6.66e-26: 93.4: 53.33		MDM4_HUMAN (4-489): 0: 531: 32.08