HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: UTRN (P46939)
Utrophin (Dystrophin-related protein 1) (DRP-1)
Gene: UTRN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36976175
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CH~fn3, CH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 976 Hs			1 3433
+	Hs
		547412 EPHA2_HUMAN (1-976): 0: 1124: 100.00		DMD_HUMAN (28-2995): 8.5e-140: 496: 32.55
+	Hs
		720156 UFO_HUMAN (294-911): 1.96e-144: 454: 24.15		UTRN_HUMAN (1-3433): 0: 1134: 100.00
+	Hs
		650082 FGFR3_HUMAN (381-889): 3.37e-136: 430: 24.65		UTRN_HUMAN (1-3433): 0: 1134: 100.00
+	Rn
		108156 INSR_RAT (371-873): 1.87e-134: 440: 29.49		UTRN_RAT (1-3433): 0: 1084: 86.83
+	Hs
		710590 EPHA2_HUMAN (1-976): 0: 1124: 100.00		DTNA_HUMAN (2849-3425): 3.27e-110: 372: 24.62
+	Hs
		463397 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		UTRN_HUMAN (1-3433): 0: 1134: 100.00
+	Hs
		710187 EPHA2_HUMAN (1-976): 0: 1124: 100.00		DYST_HUMAN (228-1504): 1.85e-30: 135: 10.97
+	Hs
		710621 EPHA3_HUMAN (24-976): 0: 1096: 50.98		DYST_HUMAN (228-1504): 1.85e-30: 135: 10.97
+	Hs
		710574 EPHA2_HUMAN (1-976): 0: 1124: 100.00		MACF1_HUMAN (1859-3031): 3.79e-13: 78.6: 9.83
+	Hs
		640149 EPHA1_HUMAN (17-967): 0: 947: 49.28		DYST_HUMAN (228-1504): 1.85e-30: 135: 10.97
+	Hs
		463299 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		DMD_HUMAN (28-2995): 8.5e-140: 496: 32.55
+	Rn
		92853 INSR_RAT (371-873): 1.87e-134: 440: 29.49		D3ZC56_RAT (797-2932): 2.97e-38: 161: 12.76
+	Hs
		463862 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		DTNA_HUMAN (2849-3425): 3.27e-110: 372: 24.62
+	Hs
		319045 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		K0754_HUMAN (1714-3020): 1.36e-30: 136: 12.93
+	Hs
		463467 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		DYST_HUMAN (228-1504): 1.85e-30: 135: 10.97
+	Hs
		174692 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		SPTN2_HUMAN (1299-2941): 1.43e-19: 99.8: 11.30
+	Hs
		463842 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		MACF1_HUMAN (1859-3031): 3.79e-13: 78.6: 9.83
+	Hs
		463457 LYN_HUMAN (607-879): 2.07e-64: 228: 42.91		SPTB2_HUMAN (1892-3433): 1.57e-11: 73.2: 9.97