HitPredict

Interactor 1: CHK1 (P34208)
Serine/threonine-protein kinase chk1 (EC 2.7.11.1) (Checkpoint kinase 1)
Gene: CHK1

Interactor 2: RAD24 (P42656)
Checkpoint signal transducer rad24
Gene: RAD24

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.730

Property	Details
Experiments	12415000, 10090724, 15585577, 37788281, 17502373, 20639859
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007095 - mitotic G2 DNA damage checkpoint signaling
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 496 Sp			1 270
+	At
		1280891 CIPKC_ARATH (7-493): 1.86e-152: 445: 24.49		14337_ARATH (3-263): 1.81e-146: 412: 69.58
+	At
		965360 CIPKC_ARATH (7-493): 1.86e-152: 445: 24.49		14332_ARATH (3-258): 1.82e-146: 412: 68.61
+	At
		788672 CIPKC_ARATH (7-493): 1.86e-152: 445: 24.49		14333_ARATH (4-255): 1.3e-145: 409: 71.65
+	At
		965291 CDPK1_ARATH (1-451): 7.63e-149: 440: 21.83		14332_ARATH (3-258): 1.82e-146: 412: 68.61
+	At
		802001 CDPK1_ARATH (1-451): 7.63e-149: 440: 21.83		14334_ARATH (2-259): 1.37e-144: 407: 67.31
+	At
		788694 CDPK1_ARATH (1-451): 7.63e-149: 440: 21.83		14335_ARATH (2-265): 1.51e-142: 402: 66.17
+	Sp
		710361 CHK1_SCHPO (1-496): 3.24e-154: 450: 100.00		RAD25_SCHPO (3-264): 4.29e-138: 391: 73.66
+	Rn
		871214 AAPK1_RAT (10-277): 1.34e-44: 166: 36.53		1433E_RAT (4-257): 3.97e-147: 413: 71.26
+	Hs
		909507 AAPK1_HUMAN (10-277): 1.38e-44: 166: 36.53		1433E_HUMAN (4-257): 3.97e-147: 413: 71.26