HitPredict

Interactor 1: KDM5A (P29375)
Lysine-specific demethylase 5A (EC 1.14.11.67) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2) ([histone H3]-trimethyl-L-lysine(4) demethylase 5A)
Gene: KDM5A

Interactor 2: MO4L1 (Q9UBU8)
Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (MRG15) (Protein MSL3-1) (Transcription factor-like protein MRG15)
Gene: MORF4L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.962

Property	Details
Experiments	26186194, 28514442, 33961781, 35636729, 17573780, 24981860, unassigned3799
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MRG~PHD
Common GO terms	GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 1690 Hs			1 362
+	Hs
		711819 KDM5A_HUMAN (1-1690): 0: 1848: 100.00		MO4L2_HUMAN (111-362): 3.83e-106: 314: 76.10
+	Hs
		833789 KDM5C_HUMAN (8-1593): 0: 1423: 48.81		MO4L1_HUMAN (1-362): 3.87e-173: 487: 100.00
+	Dm
		1481822 KDM5_DROME (13-1668): 0: 1475: 39.41		EAF3_DROME (2-361): 1.74e-104: 315: 34.89
+	Hs
		833736 KDM5C_HUMAN (8-1593): 0: 1423: 48.81		MO4L2_HUMAN (111-362): 3.83e-106: 314: 76.10
+	Mm
		953365 KDM5B_MOUSE (856-1664): 2.3e-92: 333: 19.58		MO4L1_MOUSE (1-362): 6.76e-173: 487: 99.72