Protein: KDM5
Lysine-specific demethylase 5 (EC 1.14.11.67) (Histone demethylase lid) (Jumonji/ARID domain-containing protein lid) (Protein little imaginal disks) (lid) (Retinoblastoma-binding protein 2 homolog) ([histone H3]-trimethyl-L-lysine(4) demethylase Kdm5)

Gene: KDM5
Organism: Drosophila melanogaster
Interactions: 41
UniProt ID: Q9VMJ7

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0004857 - enzyme inhibitor activity
GO:0005634 - nucleus
GO:0006325 - chromatin organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1216745

Q5U0Y0
Paired amphipathic helix protein Sin3a

3

2

Small-scale

0.827

High

1374486

HDAC1
Histone deacetylase HDAC1

3

18

Small-scale

0.827

High

381737

H3
Histone H3

2

20

Small-scale

0.768

High

1481818

Q9W410
PHD finger protein 12

2

12

Small-scale

0.754

High

1481822

EAF3
NuA4 complex subunit EAF3 homolog

2

5

Small-scale

0.754

High

701308

SUH
Suppressor of hairless protein

2

2

Small-scale

0.624

High

1481819

MYC
Myc proto-oncogene protein

2

4

Small-scale

0.624

High

356882

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

5

High-throughput

0.575

High

52100

A1Z6M0
Brahma associated protein 170kD

1

0

Small-scale

0.546

High

715281

ETS3
DNA-binding protein D-ETS-3

1

10

High-throughput

0.541

High

1172475

HR78
Nuclear hormone receptor HR78

1

20

High-throughput

0.541

High

1481527

Q9VM61
Uncharacterized protein, isoform A

1

1

High-throughput

0.541

High

1481810

Q9VMW2
Reticulon-like protein

2

2

High-throughput

0.533

High

54945

A1Z913
Vismay, isoform B

1

0

High-throughput

0.518

High

624402

CI
Transcriptional activator cubitus interruptus

1

0

High-throughput

0.518

High

1481809

Q9VMV9
Reticulon-like protein

2

1

High-throughput

0.504

High

1174776

MERH
Moesin/ezrin/radixin homolog 2

1

5

High-throughput

0.494

High

713722

ABDA
Homeobox protein abdominal-A

1

4

High-throughput

0.481

High

1014394

UBX
Homeotic protein ultrabithorax

1

9

High-throughput

0.481

High

234502

CTBP
C-terminal-binding protein

1

3

High-throughput

0.479

High

1176023

MCM4
DNA replication licensing factor MCM4

1

13

High-throughput

0.479

High

1375069

ASH2
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

15

Small-scale

0.479

High

1465534

MCM6
DNA replication licensing factor Mcm6

1

11

High-throughput

0.479

High

1481811

Q9VQ58
BRCA2-interacting transcriptional repressor EMSY

1

1

High-throughput

0.479

High

1481816

Q9W1G7
LD21576p

1

2

High-throughput

0.479

High

1481820

Q9W5E2
EG:115C2.8 protein

1

1

Small-scale

0.479

High

1481821

MCM7
DNA replication licensing factor Mcm7

1

12

High-throughput

0.479

High

1481814

Q9VRS6
Jonah 65Aiv

1

1

High-throughput

0.464

High

56997

A1ZAK9
P-element somatic inhibitor, isoform A

1

0

High-throughput

0.458

High

1465564

ASF1
Histone chaperone asf1

1

0

High-throughput

0.458

High

786398

2ABA
Protein phosphatase PP2A 55 kDa regulatory subunit

1

2

High-throughput

0.445

High

1476202

JHD1
JmjC domain-containing histone demethylation protein 1

1

6

High-throughput

0.445

High

1479060

SMBT
Polycomb protein Sfmbt

1

4

High-throughput

0.445

High

1481815

Q9VV77
Polycomb group RING finger protein 3

1

10

High-throughput

0.445

High

1476175

Q9VHG3
IP14615p

1

0

High-throughput

0.438

High

1481817

Q9W215
GEO03726p1

1

0

High-throughput

0.426

High

119204

M9NFI9
Neurabin-1

1

2

High-throughput

0.407

High

1474900

Q9VGN4
Sarcomere length short, isoform B

1

2

High-throughput

0.407

High

1481812

EXOC2
Exocyst complex component 2

1

0

High-throughput

0.282

High

1476276

Q9VHL1
LD40589p

1

0

High-throughput

0.249

Low

1481813

Q9VRI3
Uncharacterized protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025