HitPredict

Interactor 1: RYK (P34925)
Tyrosine-protein kinase RYK (EC 2.7.10.1)
Gene: RYK

Interactor 2: FAT3 (Q8TDW7)
Protocadherin Fat 3 (hFat3) (Cadherin family member 15) (FAT tumor suppressor homolog 3)
Gene: FAT3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	33961781, 21875946
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	hEGF~WIF
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 607 Hs			1 4557
+	Hs
		713862 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCD16_HUMAN (33-1352): 0: 964: 23.39
+	Hs
		411385 INSR_HUMAN (237-598): 1.43e-108: 357: 29.40		FAT1_HUMAN (1-822): 6.31e-159: 560: 23.42
+	Hs
		508295 FGFR1_HUMAN (137-599): 4.53e-145: 441: 27.29		PCDA8_HUMAN (1462-2109): 1.29e-130: 439: 21.23
+	Hs
		713899 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDG5_HUMAN (201-823): 4.57e-112: 384: 20.00
+	Hs
		713896 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDGH_HUMAN (161-823): 1.59e-108: 373: 21.45
+	Hs
		713897 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDG7_HUMAN (102-694): 4.8e-105: 363: 20.70
+	Hs
		231356 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDGC_HUMAN (4-487): 3.42e-87: 311: 17.03
+	Hs
		713898 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDG6_HUMAN (4-494): 2.18e-86: 308: 20.04
+	Hs
		523229 SRC_HUMAN (315-602): 2.06e-108: 338: 30.80		PCDG5_HUMAN (201-823): 4.57e-112: 384: 20.00
+	Hs
		713825 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		FAT4_HUMAN (4313-4493): 3.93e-12: 75.8: 7.21
+	Hs
		713871 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDH9_HUMAN (114-307): 8.03e-12: 74.3: 28.36
+	Hs
		225492 FGFR1_HUMAN (137-599): 4.53e-145: 441: 27.29		PCDH7_HUMAN (43-555): 1.39e-09: 67: 25.27
+	Hs
		713873 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		CELR2_HUMAN (3967-4068): 2.2e-10: 70: 16.35
+	Hs
		713881 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		CELR3_HUMAN (4382-4547): 2.01e-10: 70: 11.56
+	Hs
		225550 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDH7_HUMAN (43-555): 1.39e-09: 67: 25.27
+	Hs
		713790 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		PCDH1_HUMAN (117-364): 1.44e-09: 67: 25.39
+	Hs
		713880 RYK_HUMAN (1-607): 1.73e-146: 438: 100.00		CELR1_HUMAN (4259-4399): 9.1e-09: 64.6: 8.78
+	Hs
		225521 FGFR4_HUMAN (137-604): 9.44e-129: 398: 26.10		PCDH7_HUMAN (43-555): 1.39e-09: 67: 25.27
+	Hs
		523158 SRC_HUMAN (315-602): 2.06e-108: 338: 30.80		CELR2_HUMAN (3967-4068): 2.2e-10: 70: 16.35
+	Hs
		225482 MET_HUMAN (265-593): 1.87e-59: 217: 35.95		PCDH7_HUMAN (43-555): 1.39e-09: 67: 25.27