HitPredict

Interactor 1: HS71L (P34931)
Heat shock 70 kDa protein 1-like (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa protein 1-Hom) (HSP70-Hom) (Heat shock protein family A member 1L)
Gene: HSPA1L

Interactor 2: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 641 Hs			1 745
+	Hs
		504041 HSP7C_HUMAN (4-615): 0: 946: 84.80		CUL2_HUMAN (1-745): 0: 840: 100.00
+	Hs
		713963 HS71L_HUMAN (1-641): 0: 977: 100.00		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		713966 HS71L_HUMAN (1-641): 0: 977: 100.00		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		713967 HS71L_HUMAN (1-641): 0: 977: 100.00		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		713965 HS71L_HUMAN (1-641): 0: 977: 100.00		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		564073 HSP76_HUMAN (1-641): 0: 957: 79.47		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		504040 HSP7C_HUMAN (4-615): 0: 946: 84.80		CUL1_HUMAN (6-745): 0: 775: 36.24
+	Hs
		504043 HSP7C_HUMAN (4-615): 0: 946: 84.80		CUL4A_HUMAN (4-745): 0: 773: 26.86
+	Hs
		504044 HSP7C_HUMAN (4-615): 0: 946: 84.80		CUL4B_HUMAN (4-745): 0: 771: 27.79
+	Hs
		504042 HSP7C_HUMAN (4-615): 0: 946: 84.80		CUL3_HUMAN (1-745): 0: 768: 26.38
+	Hs
		714040 HS71L_HUMAN (1-641): 0: 977: 100.00		CUL5_HUMAN (7-745): 0: 627: 26.69
+	Hs
		504518 HSP7C_HUMAN (4-615): 0: 946: 84.80		CUL5_HUMAN (7-745): 0: 627: 26.69