HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: TF65 (Q04206)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: RELA

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.578

Property	Details
Experiments	9250404
Identification Methods	affinity chromatography technology, pull down, coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Hs			1 551
+	Hs
		978825 HS105_HUMAN (1-840): 0: 938: 62.95		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		714193 HSP74_HUMAN (1-840): 0: 993: 100.00		REL_HUMAN (12-523): 3.56e-165: 484: 41.64
+	Hs
		587445 HSP74_HUMAN (1-840): 0: 993: 100.00		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		1035262 HS105_HUMAN (1-840): 0: 938: 62.95		NFAC2_HUMAN (4-527): 1.26e-110: 353: 18.97
+	Hs
		503938 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		TF65_HUMAN (1-551): 0: 601: 100.00
+	Hs
		713948 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		TF65_HUMAN (1-551): 0: 601: 100.00
+	Mm
		978965 HS71A_MOUSE (571-686): 1e-17: 89.7: 23.08		TF65_MOUSE (1-551): 0: 577: 87.88
+	Hs
		503943 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		REL_HUMAN (12-523): 3.56e-165: 484: 41.64
+	Hs
		713949 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		REL_HUMAN (12-523): 3.56e-165: 484: 41.64
+	Mm
		638457 HS71A_MOUSE (571-686): 1e-17: 89.7: 23.08		NFKB1_MOUSE (7-451): 3.1e-157: 475: 30.19
+	Hs
		503415 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		587444 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		503913 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Hs
		564000 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		NFKB1_HUMAN (7-451): 2.23e-153: 465: 29.51
+	Hs
		713946 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Hs
		564058 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		RELB_HUMAN (3-461): 2.62e-154: 455: 40.00
+	Hs
		503906 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		NFKB2_HUMAN (7-409): 7.21e-137: 420: 34.75
+	Hs
		713945 HS71L_HUMAN (564-691): 7.22e-19: 93.5: 22.48		NFKB2_HUMAN (7-409): 7.21e-137: 420: 34.75
+	Hs
		564057 HSP76_HUMAN (587-690): 1.94e-16: 85.8: 22.86		NFKB2_HUMAN (7-409): 7.21e-137: 420: 34.75
+	Hs
		504030 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		NFAC2_HUMAN (4-527): 1.26e-110: 353: 18.97