HitPredict

Interactor 1: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.589

Property	Details
Experiments	17466273
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, solid phase assay
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 840 Hs			1 365
+	Hs
		213491 HSP74_HUMAN (1-840): 0: 993: 100.00		SGTA_HUMAN (6-171): 3.42e-40: 146: 20.96
+	Hs
		714148 HSP74_HUMAN (1-840): 0: 993: 100.00		PPP5_HUMAN (9-242): 1.39e-38: 145: 14.71
+	Hs
		714418 HSP74_HUMAN (1-840): 0: 993: 100.00		RPAP3_HUMAN (3-129): 5.92e-27: 114: 14.17
+	Hs
		213427 HS74L_HUMAN (1-840): 0: 959: 63.21		SGTA_HUMAN (6-171): 3.42e-40: 146: 20.96
+	Hs
		714208 HSP74_HUMAN (1-840): 0: 993: 100.00		DNJC3_HUMAN (6-326): 2.67e-25: 108: 15.69
+	At
		612328 HS701_ARATH (2-604): 0: 815: 32.57		SGT1B_ARATH (11-365): 2.91e-73: 233: 34.08
+	At
		612327 HS701_ARATH (2-604): 0: 815: 32.57		SGT1A_ARATH (33-365): 3.96e-72: 230: 34.52
+	At
		99225 HS701_ARATH (2-604): 0: 815: 32.57		OE64M_ARATH (7-124): 2.9e-40: 151: 22.03
+	At
		81973 HS701_ARATH (2-604): 0: 815: 32.57		OEP61_ARATH (10-361): 2.54e-39: 148: 12.53
+	At
		612321 HS701_ARATH (2-604): 0: 815: 32.57		OE64C_ARATH (4-124): 2.18e-38: 146: 21.49
+	Dm
		1371973 Q9VUC1_DROME (1-840): 0: 821: 42.10		Q9VPN5_DROME (1-321): 9.76e-18: 86: 10.98
+	Ce
		183700 HSP1_CAEEL (2-603): 0: 811: 31.48		STIP1_CAEEL (10-300): 1.82e-16: 81: 10.30
+	Sc
		695680 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		SGT1_YEAST (12-365): 5.06e-48: 168: 24.87
+	Sc
		549718 HSP79_YEAST (5-697): 5.63e-139: 429: 38.18		STI1_YEAST (2-145): 1.79e-14: 76.4: 23.61
+	Sc
		695109 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		PPT1_YEAST (1-128): 3.74e-15: 78.3: 16.15
+	Sc
		549717 HSP7F_YEAST (5-697): 5.7e-137: 424: 37.61		STI1_YEAST (2-145): 1.79e-14: 76.4: 23.61
+	At
		81982 HSP7E_ARATH (4-585): 4.1e-86: 289: 34.34		OEP61_ARATH (10-361): 2.54e-39: 148: 12.53
+	Hs
		213468 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		SGTA_HUMAN (6-171): 3.42e-40: 146: 20.96
+	Hs
		174578 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		OGT1_HUMAN (48-303): 5e-18: 87.6: 9.51
+	Hs
		297027 HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92		TOM70_HUMAN (3-221): 1.5e-09: 61.4: 9.29