HitPredict

Interactor 1: GRK5 (P34947)
G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)
Gene: GRK5

Interactor 2: LIPB1 (Q86W92)
Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2)
Gene: PPFIBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22952844
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~SAM_1
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 590 Hs			1 1011
+	Hs
		568724 KAPCA_HUMAN (148-500): 4.14e-142: 417: 28.61		LIPB1_HUMAN (1-1011): 7.51e-135: 433: 100.00
+	Hs
		714483 GRK5_HUMAN (1-590): 0: 550: 100.00		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		714484 GRK5_HUMAN (1-590): 0: 550: 100.00		MYH10_HUMAN (2-784): 3.65e-29: 128: 8.24
+	Hs
		626651 ARBK1_HUMAN (2-556): 3.02e-141: 427: 34.74		MRCKA_HUMAN (50-632): 1.12e-35: 149: 15.57
+	Hs
		681696 AKT1_HUMAN (68-517): 2.1e-141: 420: 29.19		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		568567 KAPCA_HUMAN (148-500): 4.14e-142: 417: 28.61		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		724784 KPCE_HUMAN (85-503): 2.08e-136: 416: 30.30		MYH9_HUMAN (2-781): 5.58e-30: 131: 7.15
+	Hs
		568568 KAPCA_HUMAN (148-500): 4.14e-142: 417: 28.61		MYH10_HUMAN (2-784): 3.65e-29: 128: 8.24
+	Hs
		610795 KAPCB_HUMAN (150-500): 3.23e-141: 415: 29.63		MYH2_HUMAN (16-806): 8.98e-26: 117: 8.00
+	Hs
		528359 KAPCB_HUMAN (150-500): 3.23e-141: 415: 29.63		MYH6_HUMAN (2-794): 8.99e-25: 114: 9.50
+	Hs
		522538 KAPCB_HUMAN (150-500): 3.23e-141: 415: 29.63		MYH1_HUMAN (185-793): 7.46e-20: 98: 9.05
+	Hs
		610802 KAPCB_HUMAN (150-500): 3.23e-141: 415: 29.63		MYH4_HUMAN (185-793): 4.55e-19: 95.7: 9.05
+	Hs
		518814 KAPCA_HUMAN (148-500): 4.14e-142: 417: 28.61		TPR_HUMAN (70-620): 8.21e-09: 62.3: 10.65