HitPredict

Interactor 1: SPT7 (P35177)
Transcriptional activator SPT7
Gene: SPT7

Interactor 2: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21734642
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1332 Sc			1 463
+	Sc
		715416 SPT7_YEAST (1-1332): 0: 1183: 100.00		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Mm
		888099 BRD8_MOUSE (72-588): 4.29e-83: 295: 16.03		RUVB1_MOUSE (2-461): 0: 682: 67.83
+	Dm
		631322 BRM_DROME (199-648): 4.73e-58: 223: 10.35		RUVB1_DROME (15-461): 0: 648: 66.89
+	Sc
		969410 RSC4_YEAST (244-866): 6.47e-49: 187: 13.58		RUVB1_YEAST (1-463): 0: 682: 100.00
+	Dm
		1362521 Q9VC36_DROME (211-821): 1.64e-52: 205: 13.17		RUVB1_DROME (15-461): 0: 648: 66.89
+	Hs
		1270840 CBP_HUMAN (330-549): 7.1e-40: 164: 18.94		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Sc
		969448 RSC4_YEAST (244-866): 6.47e-49: 187: 13.58		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Hs
		1327673 BRD8_HUMAN (122-572): 3.59e-26: 119: 12.34		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Sc
		975957 GCN5_YEAST (435-548): 5.76e-20: 96.4: 29.83		RUVB1_YEAST (1-463): 0: 682: 100.00
+	Hs
		1327672 BRD8_HUMAN (122-572): 3.59e-26: 119: 12.34		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Sc
		976004 GCN5_YEAST (435-548): 5.76e-20: 96.4: 29.83		RUVB2_YEAST (15-463): 0: 622: 41.15