HitPredict

Interactor 1: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Interactor 2: DJB12 (Q9NXW2)
DnaJ homolog subfamily B member 12
Gene: DNAJB12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 375
+	Hs
		717552 PDIA3_HUMAN (1-505): 4.08e-163: 473: 100.00		DJB14_HUMAN (1-375): 1.41e-121: 358: 51.32
+	Hs
		452414 PDIA1_HUMAN (3-482): 3.49e-117: 356: 33.06		DJB12_HUMAN (1-375): 1.34e-139: 403: 100.00
+	Hs
		717604 PDIA3_HUMAN (1-505): 4.08e-163: 473: 100.00		DJC18_HUMAN (51-375): 4.47e-83: 259: 39.71
+	Hs
		452341 PDIA1_HUMAN (3-482): 3.49e-117: 356: 33.06		DJB14_HUMAN (1-375): 1.41e-121: 358: 51.32
+	Hs
		717631 PDIA3_HUMAN (1-505): 4.08e-163: 473: 100.00		DJB11_HUMAN (101-368): 1.56e-46: 164: 23.49
+	Hs
		717630 PDIA3_HUMAN (1-505): 4.08e-163: 473: 100.00		DNJB9_HUMAN (99-247): 1.08e-41: 147: 32.89
+	Hs
		679072 PDIA3_HUMAN (1-505): 4.08e-163: 473: 100.00		DNJB1_HUMAN (109-223): 3.49e-40: 146: 43.70
+	Hs
		452400 PDIA1_HUMAN (3-482): 3.49e-117: 356: 33.06		DJC18_HUMAN (51-375): 4.47e-83: 259: 39.71
+	Hs
		452429 PDIA1_HUMAN (3-482): 3.49e-117: 356: 33.06		SEC63_HUMAN (87-373): 4.78e-51: 183: 18.61
+	Hs
		452423 PDIA1_HUMAN (3-482): 3.49e-117: 356: 33.06		DJB11_HUMAN (101-368): 1.56e-46: 164: 23.49
+	Hs
		566853 PDIA4_HUMAN (376-494): 1.94e-23: 106: 34.71		DJB12_HUMAN (1-375): 1.34e-139: 403: 100.00
+	Hs
		452422 PDIA1_HUMAN (3-482): 3.49e-117: 356: 33.06		DNJB9_HUMAN (99-247): 1.08e-41: 147: 32.89
+	Hs
		566766 PDIA4_HUMAN (376-494): 1.94e-23: 106: 34.71		DJB14_HUMAN (1-375): 1.41e-121: 358: 51.32
+	Hs
		566839 PDIA4_HUMAN (376-494): 1.94e-23: 106: 34.71		DJC18_HUMAN (51-375): 4.47e-83: 259: 39.71
+	Hs
		1312081 DJC10_HUMAN (11-244): 2.95e-32: 133: 16.67		DJB11_HUMAN (101-368): 1.56e-46: 164: 23.49
+	Hs
		566868 PDIA4_HUMAN (376-494): 1.94e-23: 106: 34.71		SEC63_HUMAN (87-373): 4.78e-51: 183: 18.61
+	Hs
		566864 PDIA4_HUMAN (376-494): 1.94e-23: 106: 34.71		DJB11_HUMAN (101-368): 1.56e-46: 164: 23.49
+	Rn
		1193309 DJC10_RAT (28-128): 3.16e-21: 99.5: 31.43		DJB11_RAT (101-368): 4.1e-46: 163: 23.49
+	Rn
		1021809 DJC10_RAT (28-128): 3.16e-21: 99.5: 31.43		DNJB9_RAT (102-239): 6.84e-46: 158: 33.81
+	Hs
		566863 PDIA4_HUMAN (376-494): 1.94e-23: 106: 34.71		DNJB9_HUMAN (99-247): 1.08e-41: 147: 32.89