HitPredict

Interactor 1: PDIA4 (P13667)
Protein disulfide-isomerase A4 (EC 5.3.4.1) (Endoplasmic reticulum resident protein 70) (ER protein 70) (ERp70) (Endoplasmic reticulum resident protein 72) (ER protein 72) (ERp-72) (ERp72)
Gene: PDIA4

Interactor 2: DNJB9 (Q9UBS3)
DnaJ homolog subfamily B member 9 (Endoplasmic reticulum DNA J domain-containing protein 4) (ER-resident protein ERdj4) (ERdj4) (Microvascular endothelial differentiation gene 1 protein) (Mdg-1)
Gene: DNAJB9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0034976 - response to endoplasmic reticulum stress
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 645 Hs			1 223
+	Hs
		566766 PDIA4_HUMAN (1-645): 0: 564: 100.00		DJB14_HUMAN (10-174): 6.92e-47: 160: 31.74
+	Hs
		566864 PDIA4_HUMAN (1-645): 0: 564: 100.00		DJB11_HUMAN (4-109): 1.25e-44: 154: 42.06
+	Hs
		566853 PDIA4_HUMAN (1-645): 0: 564: 100.00		DJB12_HUMAN (2-177): 4.12e-44: 153: 26.97
+	Hs
		566882 PDIA4_HUMAN (1-645): 0: 564: 100.00		DJC16_HUMAN (10-135): 2.92e-41: 150: 36.15
+	Hs
		566866 PDIA4_HUMAN (1-645): 0: 564: 100.00		DNJ5B_HUMAN (24-203): 4.95e-44: 148: 27.47
+	Rn
		1021809 DJC10_RAT (54-279): 8.37e-45: 173: 20.94		DNJB9_RAT (1-223): 3.96e-69: 212: 92.38
+	Hs
		452422 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		DNJB9_HUMAN (1-223): 3.64e-71: 218: 100.00
+	Hs
		717630 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		DNJB9_HUMAN (1-223): 3.64e-71: 218: 100.00
+	Hs
		1334140 TXND5_HUMAN (176-391): 3.68e-29: 122: 22.18		DNJB9_HUMAN (1-223): 3.64e-71: 218: 100.00
+	Hs
		1312081 DJC10_HUMAN (54-285): 1.12e-46: 178: 21.25		DJB11_HUMAN (4-109): 1.25e-44: 154: 42.06
+	Rn
		1193309 DJC10_RAT (54-279): 8.37e-45: 173: 20.94		DJB11_RAT (4-109): 1.21e-44: 154: 42.06
+	Hs
		452341 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		DJB14_HUMAN (10-174): 6.92e-47: 160: 31.74
+	Hs
		452423 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		DJB11_HUMAN (4-109): 1.25e-44: 154: 42.06
+	Hs
		717552 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		DJB14_HUMAN (10-174): 6.92e-47: 160: 31.74
+	Hs
		452414 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		DJB12_HUMAN (2-177): 4.12e-44: 153: 26.97
+	Hs
		679072 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		DNJB1_HUMAN (24-213): 1.29e-46: 158: 28.00
+	Hs
		452443 PDIA1_HUMAN (4-164): 1.71e-31: 130: 27.27		DJC16_HUMAN (10-135): 2.92e-41: 150: 36.15
+	Hs
		717631 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		DJB11_HUMAN (4-109): 1.25e-44: 154: 42.06
+	Hs
		717622 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		DJB12_HUMAN (2-177): 4.12e-44: 153: 26.97
+	Hs
		717649 PDIA3_HUMAN (5-188): 1.81e-29: 124: 27.04		DJC16_HUMAN (10-135): 2.92e-41: 150: 36.15