Interactor 1: CCND3 (P30281)
G1/S-specific cyclin-D3
Gene: CCND3
Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.42 | 1.00 | 0.653 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 35512704 |
| Identification Methods | split luciferase complementation, pull down |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cyclin_C~Pkinase, Cyclin_N~Pkinase |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction and 2 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
