HitPredict

Interactor 1: PHB1 (P35232)
Prohibitin 1
Gene: PHB1

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	27025967
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0007005 - mitochondrion organization GO:0007165 - signal transduction GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 272 Hs			1 618
+	Hs
		1220638 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		MIRO2_HUMAN (1-618): 0: 792: 100.00
+	Hs
		718978 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		MIRO1_HUMAN (1-618): 0: 763: 59.65
+	Hs
		545232 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		718676 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		718752 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		718731 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		894352 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		951263 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		925555 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		545212 STOM_HUMAN (1-265): 6.57e-68: 213: 17.91		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		646156 STOM_HUMAN (1-265): 6.57e-68: 213: 17.91		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		718708 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		914308 PHB2_HUMAN (6-267): 1.38e-85: 259: 50.57		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		718710 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		718686 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		719159 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		120322 PHB1_HUMAN (1-272): 7.06e-92: 274: 100.00		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		436164 STOM_HUMAN (1-265): 6.57e-68: 213: 17.91		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120306 STOM_HUMAN (1-265): 6.57e-68: 213: 17.91		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		564417 STOM_HUMAN (1-265): 6.57e-68: 213: 17.91		RHOQ_HUMAN (5-169): 2.02e-10: 62.8: 26.26