HitPredict

Interactor 1: B3KPL7 (B3KPL7)
cDNA FLJ31926 fis, clone NT2RP7005502, highly similar to Homo sapiens AFG3 ATPase family gene 3-like 1 (yeast) (AFG3L1), transcript variant 1, mRNA (cDNA FLJ33974 fis, clone DFNES2002550, highly similar to Homo sapiens AFG3 ATPase family gene 3-like 1 (yeast) (AFG3L1), transcript variant 1, mRNA)
Gene: B3KPL7

Interactor 2: UBE3A (Q05086)
Ubiquitin-protein ligase E3A (EC 2.3.2.26) (E6AP ubiquitin-protein ligase) (HECT-type ubiquitin transferase E3A) (Human papillomavirus E6-associated protein) (Oncogenic protein-associated protein E6-AP) (Renal carcinoma antigen NY-REN-54)
Gene: UBE3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 122 Hs			1 875
+	Hs
		906999 PRS8_HUMAN (3-118): 7.43e-48: 159: 29.03		UBE3A_HUMAN (1-875): 0: 1058: 100.00
+	Hs
		906816 PRS4_HUMAN (3-112): 5.12e-46: 155: 31.36		UBE3A_HUMAN (1-875): 0: 1058: 100.00
+	Hs
		798641 PRS6B_HUMAN (3-112): 1.77e-45: 153: 27.12		UBE3A_HUMAN (1-875): 0: 1058: 100.00
+	Hs
		913250 PRS10_HUMAN (3-112): 9.44e-46: 153: 27.12		UBE3A_HUMAN (1-875): 0: 1058: 100.00
+	Hs
		730242 PRS7_HUMAN (2-96): 3.28e-40: 139: 34.38		UBE3A_HUMAN (1-875): 0: 1058: 100.00
+	Hs
		907035 PRS8_HUMAN (3-118): 7.43e-48: 159: 29.03		HERC3_HUMAN (139-874): 0: 582: 26.85
+	Hs
		798669 PRS6B_HUMAN (3-112): 1.77e-45: 153: 27.12		HERC3_HUMAN (139-874): 0: 582: 26.85
+	Hs
		730265 PRS7_HUMAN (2-96): 3.28e-40: 139: 34.38		HERC3_HUMAN (139-874): 0: 582: 26.85
+	Sc
		636637 CDC48_YEAST (3-118): 1.34e-43: 153: 27.42		RSP5_YEAST (310-873): 0: 554: 25.85
+	Hs
		907164 PRS8_HUMAN (3-118): 7.43e-48: 159: 29.03		SMUF1_HUMAN (405-872): 1.32e-175: 528: 27.04
+	Hs
		798765 PRS6B_HUMAN (3-112): 1.77e-45: 153: 27.12		SMUF1_HUMAN (405-872): 1.32e-175: 528: 27.04
+	Hs
		907081 PRS8_HUMAN (3-118): 7.43e-48: 159: 29.03		HUWE1_HUMAN (523-874): 5.96e-53: 203: 33.97
+	Hs
		907040 PRS8_HUMAN (3-118): 7.43e-48: 159: 29.03		UBE3C_HUMAN (453-872): 2.23e-52: 200: 32.27
+	Hs
		906870 PRS4_HUMAN (3-112): 5.12e-46: 155: 31.36		HUWE1_HUMAN (523-874): 5.96e-53: 203: 33.97
+	Hs
		798705 PRS6B_HUMAN (3-112): 1.77e-45: 153: 27.12		HUWE1_HUMAN (523-874): 5.96e-53: 203: 33.97
+	Hs
		913303 PRS10_HUMAN (3-112): 9.44e-46: 153: 27.12		HUWE1_HUMAN (523-874): 5.96e-53: 203: 33.97
+	Hs
		798672 PRS6B_HUMAN (3-112): 1.77e-45: 153: 27.12		UBE3C_HUMAN (453-872): 2.23e-52: 200: 32.27
+	Hs
		913273 PRS10_HUMAN (3-112): 9.44e-46: 153: 27.12		UBE3C_HUMAN (453-872): 2.23e-52: 200: 32.27
+	Hs
		730302 PRS7_HUMAN (2-96): 3.28e-40: 139: 34.38		HUWE1_HUMAN (523-874): 5.96e-53: 203: 33.97
+	Hs
		730268 PRS7_HUMAN (2-96): 3.28e-40: 139: 34.38		UBE3C_HUMAN (453-872): 2.23e-52: 200: 32.27