HitPredict

Interactor 1: MCM4 (P30665)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Cell division control protein 54)
Gene: MCM4

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30104407, 19661920, 22199229
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 933 Sc			1 136
+	Sc
		721366 MCM4_YEAST (1-933): 0: 953: 100.00		CENPA_YEAST (24-134): 1.34e-40: 136: 53.04
+	Hs
		755682 MCM4_HUMAN (30-926): 0: 826: 41.57		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		755688 MCM4_HUMAN (30-926): 0: 826: 41.57		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		755665 MCM4_HUMAN (30-926): 0: 826: 41.57		CENPA_HUMAN (9-133): 1.33e-44: 144: 47.73
+	Hs
		887960 MCM2_HUMAN (31-902): 0: 714: 26.03		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		887972 MCM2_HUMAN (31-902): 0: 714: 26.03		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Hs
		888100 MCM2_HUMAN (31-902): 0: 714: 26.03		H31T_HUMAN (1-136): 1.42e-59: 181: 86.03
+	Hs
		888146 MCM2_HUMAN (31-902): 0: 714: 26.03		H32_HUMAN (1-136): 2.01e-59: 181: 88.97
+	Hs
		755879 MCM5_HUMAN (155-909): 0: 703: 28.42		H31_HUMAN (1-136): 1.22e-60: 184: 88.97
+	Hs
		755881 MCM5_HUMAN (155-909): 0: 703: 28.42		H33_HUMAN (1-136): 3.3e-60: 183: 90.44
+	Mm
		999020 MCM2_MOUSE (47-902): 0: 702: 25.82		H31_MOUSE (1-136): 1.22e-60: 184: 88.97
+	Mm
		1017343 MCM2_MOUSE (47-902): 0: 702: 25.82		H33_MOUSE (1-136): 3.3e-60: 183: 90.44
+	Hs
		755938 MCM5_HUMAN (155-909): 0: 703: 28.42		H31T_HUMAN (1-136): 1.42e-59: 181: 86.03
+	Hs
		755967 MCM5_HUMAN (155-909): 0: 703: 28.42		H32_HUMAN (1-136): 2.01e-59: 181: 88.97
+	Mm
		1016749 MCM2_MOUSE (47-902): 0: 702: 25.82		H32_MOUSE (1-136): 2.01e-59: 181: 88.97
+	Hs
		755954 MCM5_HUMAN (155-909): 0: 703: 28.42		H37_HUMAN (1-136): 1.44e-57: 176: 86.77
+	Hs
		755960 MCM5_HUMAN (155-909): 0: 703: 28.42		H3C_HUMAN (1-136): 1.76e-57: 176: 86.03
+	Sc
		917048 MCM6_YEAST (106-930): 0: 696: 23.84		H3_YEAST (1-136): 1.85e-55: 171: 100.00
+	Hs
		883483 MCM2_HUMAN (31-902): 0: 714: 26.03		CENPA_HUMAN (9-133): 1.33e-44: 144: 47.73
+	Sc
		779291 MCM6_YEAST (106-930): 0: 696: 23.84		CENPA_YEAST (24-134): 1.34e-40: 136: 53.04