HitPredict

Interactor 1: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Interactor 2: NECT3 (Q9NQS3)
Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113)
Gene: NECTIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32900848
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 549
+	Hs
		602285 CD9_HUMAN (1-234): 3.88e-53: 172: 43.59		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		887918 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		905517 TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67		SDK2_HUMAN (39-476): 2.32e-34: 140: 12.92
+	Hs
		602263 CD9_HUMAN (1-234): 3.88e-53: 172: 43.59		SDK2_HUMAN (39-476): 2.32e-34: 140: 12.92
+	Hs
		888000 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		ROBO1_HUMAN (264-548): 5.78e-25: 112: 10.39
+	Hs
		887903 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CADM4_HUMAN (3-281): 9.17e-23: 102: 14.95
+	Hs
		326081 TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48		SDK2_HUMAN (39-476): 2.32e-34: 140: 12.92
+	Hs
		887951 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		CADM1_HUMAN (4-255): 1.27e-18: 90.4: 14.90
+	Hs
		602297 CD9_HUMAN (1-234): 3.88e-53: 172: 43.59		ROBO1_HUMAN (264-548): 5.78e-25: 112: 10.39
+	Hs
		2727 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		A0A0C4DG49_HUMAN (2-269): 4.23e-10: 63.8: 13.33
+	Hs
		545090 CD81_HUMAN (1-236): 6.2e-63: 197: 100.00		PVR_HUMAN (2-269): 4.78e-10: 63.8: 13.33
+	Hs
		1199563 TSN33_HUMAN (9-233): 7.63e-51: 168: 22.78		TITIN_HUMAN (65-499): 6.04e-09: 61.3: 9.13