HitPredict

Interactor 1: APJ (P35414)
Apelin receptor (Angiotensin receptor-like 1) (G-protein coupled receptor APJ) (G-protein coupled receptor HG11)
Gene: APLNR

Interactor 2: AB17B (Q5VST6)
Alpha/beta hydrolase domain-containing protein 17B (Abhydrolase domain-containing protein 17B) (EC 3.1.2.22)
Gene: ABHD17B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 380 Hs			1 288
+	Hs
		723377 APJ_HUMAN (1-380): 8.93e-97: 294: 100.00		AB17A_HUMAN (1-287): 3.1e-107: 315: 73.29
+	Hs
		1030953 GPR17_HUMAN (20-352): 8.49e-83: 258: 30.84		AB17B_HUMAN (1-288): 1.86e-109: 320: 100.00
+	Hs
		895647 CXCR4_HUMAN (4-325): 2.98e-79: 249: 27.69		AB17B_HUMAN (1-288): 1.86e-109: 320: 100.00
+	Hs
		723050 OPRM_HUMAN (4-373): 1.48e-67: 220: 23.99		AB17B_HUMAN (1-288): 1.86e-109: 320: 100.00
+	Hs
		781068 OPRX_HUMAN (27-343): 2.82e-67: 218: 26.73		AB17B_HUMAN (1-288): 1.86e-109: 320: 100.00
+	Hs
		895676 CXCR4_HUMAN (4-325): 2.98e-79: 249: 27.69		ABD12_HUMAN (18-287): 5.73e-63: 205: 20.97
+	Hs
		429112 ADRB2_HUMAN (1-349): 2e-70: 228: 20.47		MGLL_HUMAN (52-272): 9.9e-50: 168: 15.36
+	Hs
		1044522 5HT4R_HUMAN (25-378): 1.89e-67: 219: 20.27		MGLL_HUMAN (52-272): 9.9e-50: 168: 15.36